化合物简介
Trimetazidine is a drug for angina pectoris sold under the brand name Vastarel MR. Trimetazidine is described as the first cytoprotective anti-ischemic agent developed and marketed by Laboratoires Servier (France). Trimetazidine is an anti-ischemic (anti-anginal) metabolic agent, which improves myocardial glucose utilization through inhibition of fatty acid metabolism, also known as fatty acid oxidation inhibitor.
基本信息
中文名称
曲美他嗪
英文名称
Trimetazidine
中文别名
1-(2,3,4-三甲氧基苄基)哌嗪
英文别名
1-[(2,3,4-trimethoxyphenyl)methyl]piperazine、Vastarel、1-(2,3,4-trimethoxybenzyl)piperazine
CAS号
5011-34-7
分子式
C14H22N2O3
分子量
266.336
精确质量
266.163
PSA
42.96
LOGP
1.3843
编号系统
MDL号
MFCD00243086
物化性质
外观与性状
白色或灰白色结晶粉末
密度
1.092 g/cm3
沸点
364ºC at 760 mmHg
熔点
200 - 205ºC
闪点
174ºC
储存条件
Store in original container in a cool dark place.
安全信息
海关编码
2933599090
危险品标志
Xi