化合物简介
Taurochenodeoxycholic acid is a bile acid formed in the liver of most species, including humans, by conjugation of chenodeoxycholic acid with taurine. It is secreted into bile and then into intestine. It is usually ionized at physiologic pH, although it can be crystallized as the sodium salt. It acts as detergent to solubilize fats in the small intestine and is itself absorbed by active transport in the terminal ileum. It is used as a cholagogue and choleretic.
基本信息
中文名称
牛磺鹅去氧胆酸
英文名称
taurochenodeoxycholic acid
中文别名
英文别名
Chenodeoxycholoyltaurine、12-Desoxycholyltaurine、Taurochenodeoxycholic acid、12-Deoxycholyltaurine、Chenyltaurine、[3H]-Chenodeoxycholyltaurine、Chenodeoxycholyltaurine、Chenodeoxytaurocholic acid、Taurochenodesoxycholic acid
CAS号
516-35-8
分子式
C26H45NO6S
分子量
499.704
精确质量
499.297
PSA
132.31
LOGP
4.869
编号系统
UNII
651KU15938
物化性质
密度
1.216g/cm3
折射率
1.552