化合物简介
Tipepidine (INN) (brand names Asverin, Antupex, Asvelik, Asvex, Bitiodin, Cofdenin A, Hustel, Nodal, Sotal), also known as tipepidine hibenzate (JAN), is a synthetic, non-opioid antitussive and expectorant of the thiambutene class. It acts as an inhibitor of G protein-coupled inwardly-rectifying potassium channels (GIRKs). The drug was discovered in the 1950s, and was developed in Japan in 1959. It is used as the hibenzate and citrate salts.
基本信息
中文名称
替培啶
英文名称
3-(dithiophen-2-ylmethylidene)-1-methylpiperidine
中文别名
英文别名
3-(di-thiophen-2-yl-methylene)-1-methyl-piperidine、Piperidine, 3-(di-2-thienylmethylene)-1-methyl-、Tipepidine、(1-Methyl-3-piperidylidene)di(2-thienyl)methane、Tipedine、3-(Di-[2]thienyl-methylen)-1-methyl-piperidin、Tipepidina [INN-Spanish]、Tipepidinum [INN-Latin]、3-(di-[2]thienyl-methylene)-1-methyl-piperidine、(1-Methyl-3-piperidyliden)di-2-thienylmethan-embonat、Asverin、AT 327、CR/662、Tipepidine [INN:DCF]、Bitiodin
CAS号
5169-78-8
分子式
C15H17NS2
分子量
275.432
精确质量
275.08
PSA
59.72
LOGP
4.275
编号系统
UNII
2260ZP67IT
物化性质
储存条件
库房通风低温干燥,与氧化剂、酸类分开存放
安全信息
海关编码
2934999090
