化合物简介
Medroxyprogesterone (INN, BAN), also known as 17α-hydroxy-6α-methylprogesterone, and abbreviated as MP, is a steroidal progestin drug which was never marketed for use in humans. An acylated derivative, medroxyprogesterone acetate (MPA), is clinically used as a pharmaceutical medicine. Compared to MPA, MP is over two orders of magnitude less potent as a progestogen. As such, MP itself is not used clinically, though it has seen limited use in veterinary medicine under the trade name Controlestril in France. In addition, it is a metabolite of MPA.
基本信息
中文名称
甲羟孕酮
英文名称
medroxyprogesterone
中文别名
6Alpha-甲基-17Alpha-羟孕酮、甲孕酮、17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione、6α-甲基-17α-羟孕酮
英文别名
Medroxyprogesteron、Medroxyprogesteronum、Hydroxymethylprogesterone、17alpha-Hydroxy-6alpha-methylprogesterone、(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one、Medroxyprogesterone、Medroxy Progesterone、Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6α)-、17-Hydroxy-6alpha-methylprogesterone、Medroxiprogesteronum、Medrossiprogesterone、Farlutal
CAS号
520-85-4
分子式
C22H32O3
分子量
344.488
精确质量
344.235
PSA
54.37
LOGP
4.0844
编号系统
UNII
HSU1C9YRES
物化性质
密度
1.13g/cm3
沸点
488ºC at 760mmHg
熔点
220-223.5ºC
闪点
263ºC
折射率
1.538
储存条件
Refrigerator
安全信息
危险类别码
R48; R63; R68
危险品标志
Xn
危险标志
GHS08
危险性描述
H361
信号词
Warning
危险性防范说明
P281
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