百科

Fagomine; 桑叶生物碱; (2R,3R,4R)-2-羟甲基哌啶-3,4-二醇

CAS号：53185-12-9

英文名：(2R,3R,4R)-2-(hydroxymethyl)piperidine-3,4-diol

分子式

C6H13NO3

熔点

密度

分子量

147.172

沸点

溶解度

信号词

危险品标志

若想填写更详细的询价信息，请点击进入询价页面

点我

化合物简介

Fagomine is an iminosugar which may reduce the risks of developing insulin resistance and becoming overweight. Also lowers blood glucose and modulates bacterial adhesion.

基本信息

中文名称

Fagomine; 桑叶生物碱; (2R,3R,4R)-2-羟甲基哌啶-3,4-二醇

英文名称

(2R,3R,4R)-2-(hydroxymethyl)piperidine-3,4-diol

中文别名

英文别名

1,5-imino-1,2,5-trideoxy-D-arabino hexitol、Fagomine、1,2,5-Trideoxy-1,5-imino-D-arabino-hexitol

CAS号

53185-12-9

分子式

C6H13NO3

分子量

147.172

精确质量

147.09

PSA

72.72

LOGP

-1.6088

安全信息

海关编码

2933399090

合成路线

1333312-83-6

(3aR,4R,7aR)-methyl octahydro-1,1,3,3-tetramethyl-6-oxo-[1,2,5]oxadisilolo[3,4-c]pyridine-4-carboxylate

53185-12-9

Fagomine; 桑叶生物碱; (2R,3R,4R)-2-羟甲基哌啶-3,4-二醇

上游原料

共找到52个上游原料 >

1129725-82-1

(2S,3R,4R)-1-benzyl-3,4-bis(benzyloxy)-2-(benzyloxymethyl)piperidine

943135-38-4

(2R,3R)-5-[N-(tert-butoxycarbonyl)amino]-2,3-dibenzyloxypentan-1-ol

1349697-03-5

2-((4R,5R,6R)-5-((tert-butyldimethylsilyl)oxy)-4-(((tert-butyldimethylsilyl)oxy)methyl)-2-phenyl-5,6-dihydro-4H-1,3-oxazin-6-yl)ethan-1-ol

531503-07-8

(1S,2R,6R)-2-hydroxymethyl-7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylic acid tert-butyl ester

143706-32-5

2-Desoxy-L-threo-5-hexulosonitril

98260-62-9

methyl 3-O-benzyl-2-O-trifluoromethanesulphonyl-α-D-glucofuranoside-5,6-carbonate

上游原料

(2S,3R,4R)-1-benzyl-3,4-bis(benzyloxy)-2-(benzyloxymethyl)piperidine (2R,3R)-5-[N-(tert-butoxycarbonyl)amino]-2,3-dibenzyloxypentan-1-ol (1S,2R,6R)-2-hydroxymethyl-7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylic acid tert-butyl ester 2-Desoxy-L-threo-5-hexulosonitril methyl 3-O-benzyl-2-O-trifluoromethanesulphonyl-α-D-glucofuranoside-5,6-carbonate (R)-methyl 2-((tert-butyloxycarbonyl)amino)-2-((3R,4R)-4-(2-methoxy-2-oxoethyl)-2,2,5,5-tetramethyl-1,2,5-oxadisilolan-3-yl)acetate (S)-3-((R)-2-azido-2-((3R,4R)-4-(2-((S)-4-isopropyl-2-oxooxazolidin-3-yl)-2-oxoethyl)-2,2,5,5-tetramethyl-1,2,5-oxadisilolan-3-yl)acetyl)-4-isopropyloxazolidin-2-one methyl 3-O-benzyl-N-benzyloxycarbonyl-2,6-imino-2,5,6-trideoxy-α-D-lyxo-hexofuranoside ethyl (4R,5R)-7-[N-(tert-butoxycarbonyl)amino]-4,5-dibenzyloxy-2-heptenoate 2-甲基-2-丙基[(3E)-5-羟基-3-戊烯-1-基]氨基甲酸酯 (2R,3R)-5-[N-(tert-butoxycarbonyl)amino]-1-(tert-butyl-dimethylsilyloxy)pentan-2,3-diol benzyl (2S,3R,4R)-3-(benzyloxy)-2-formyl-4-hydroxypiperidine-1-carboxylate methyl 3-O-benzyl-N-benzyloxycarbonyl-2,6-imino-2,5,6-trideoxy-β-D-lyxo-hexofuranoside (2S,3R)-5-[N-(tert-butoxycarbonyl)amino]-2,3-dibenzyloxypentanal (4aR,8R,8aR)-tert-butyl hexahydro-8-hydroxy-2,2-dimethyl[1,3]dioxino[5,4-b]pyridine-5-carboxylate (2R,3R,4R)-N-tert-butoxycarbonyl-3,4-dibenzyloxy-2-vinylpiperidine 2-((4R,5R,6R)-5-((tert-butyldimethylsilyl)oxy)-4-(((tert-butyldimethylsilyl)oxy)methyl)-2-phenyl-5,6-dihydro-4H-1,3-oxazin-6-yl)ethyl methanesulfonate (4S,4'S)-3,3'-(2,2'-((3R,4R)-2,2,5,5-tetramethyl-1,2,5-oxadisilolane-3,4-diyl)bis(acetyl))bis(4-isopropyloxazolidin-2-one) N-苄氧羰基-3-氨基丙醛 (4R,5R,6R)-5-(tert-butyldimethylsilyloxy)-4-((tert-butyldimethylsilyloxy)methyl)-2-phenyl-6-vinyl-5,6-dihydro-4H-1,3-oxazine (3S,4R)-6-[(benzyloxycarbonyl)amino]-5,6-dideoxy-2-hexulose (4R,5R)-7-[N-(tert-butoxycarbonyl)amino]-4,5-dibenzyloxy-2-hepten-1-ol (2R,3R,4R)-benzyl 3,4-bis(benzyloxy)-2-(hydroxymethyl)piperidine-1-carboxylate (4aR,8aS)-2,2-dimethyl-4,4a,6,8a-tetrahydro[1,3]dioxino[5,4-b]pyridine-5-carboxylic acid tert-butyl ester (1R,2R,6S)-2-(tert-butyldiphenylsilanyloxymethyl)-7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylic acid tert-butyl ester (4S,5R)-allyl-(2,2-dimethyl-4-vinyl[1,3]dioxan-5-yl)carbamic acid tert-butyl ester 二丙酮-D-葡萄糖 N-((2R,3S,E)-1-(tert-butyldimethylsilyloxy)-6-chloro-3-hydroxyhex-4-en-2-yl)benzamide (2R,3R,4R)-3-(tert-butyldimethylsilyloxy)-2-((tert-butyldimethylsilyloxy)methyl)piperidin-4-ol methyl N-benzyloxycarbonyl-3-O-benzyl-2,6-dideoxy-2,6-imino-5-O-phenyloxythiocarbonyl-α-D-mannofuranoside (S)-6-hydroxymethyl-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 5-[N-(tert-butoxycarbonyl)amino]-1-(tert-butyl-dimethylsilyloxy)-2-pentene methyl N-benzyloxycarbonyl-3-O-benzyl-2,6-dideoxy-2,6-imino-α-D-mannofuranoside 4-O-benzyl-N-benzyloxycarbonyl-1,5-imino-1,2,5-trideoxy-D-arabino-hexitol (3aR,4R,7aR)-methyl octahydro-1,1,3,3-tetramethyl-6-oxo-[1,2,5]oxadisilolo[3,4-c]pyridine-4-carboxylate (S)-6-(tert-butyldiphenylsilanyloxymethyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester (S)-3-((R)-2-((tert-butyloxycarbonyl)amino)-2-((3R,4R)-4-(2-((S)-4-isopropyl-2-oxooxazolidin-3-yl)-2-oxoethyl)-2,2,5,5-tetramethyl-1,2,5-oxadisilolan-3-yl)acetyl)-4-isopropyloxazolidin-2-one (S)-but-3-enyl[1-(tert-butyldiphenylsilanyloxymethyl)allyl]carbamic acid tert-butyl ester (1S,4R,5S,7S,8R)-benzyl 8-(benzyloxy)-7-methoxy-4-(((trifluoromethyl)sulfonyl)oxy)-6-oxa-2-azabicyclo[3.2.1]octane-2-carboxylate 3,4-dibenzyloxy-1,5-imino-1,2,5-trideoxy-D-arabino hexitol 3-O-苄基-1,2:5,6-O-双异丙叉-α-D-呋喃葡萄糖 (2R,3R,4R)-(N-tert-butoxycarbonyl-3,4-dibenzyloxy-2-piperidinyl)methanol (2R,3R)-5-[N-(tert-butoxycarbonyl)amino]-2,3-dibenzyloxy-1-(tert-butyl-dimethylsilyloxy)pentane methyl 3-O-benzyl-2,6-imino-2,5,6-trideoxy-D-lyxo-hexofuranoside 1,2,5-trideoxy-4-O-(β-D-glucopyranosyl)-1,5-imino-D-arabinohexitol (R)-2-((2R,3R,4S,5S)-4-azido-3-(benzyloxy)-5-methoxytetrahydrofuran-2-yl)-2-hydroxyethyl 4-methylbenzenesulfonate (1R,3aR,7aR,8R)-6,6-dimethylhexahydro-1,5,7-trioxa-3-azacyclopropa[a]naphthalene-3-carboxylic acid tert-butyl ester (R,E)-N-(1-(tert-butyldimethylsilyloxy)-6-chloro-3-oxohex-4-en-2-yl)benzamide