化合物简介
Hordenine (N,N-dimethyltyramine) is an alkaloid of the phenethylamine class that occurs naturally in a variety of plants, taking its name from one of the most common, barley (Hordeum species). Chemically, hordenine is the N-methyl derivative of N-methyltyramine, and the N,N-dimethyl derivative of the well-known biogenic amine tyramine, from which it is biosynthetically derived and with which it shares some pharmacological properties (see below). Currently, hordenine is widely sold as an ingredient of nutritional supplements, with the claims that it is a stimulant of the central nervous system, and has the ability to promote weight loss by enhancing metabolism. In experimental animals, given sufficiently large doses parenterally (i.e. by injection), hordenine does produce an increase in blood pressure, as well as other disturbances of the cardio-vascular, respiratory and nervous systems. These effects are generally not reproduced by oral administration of the drug in test animals, and there are virtually no scientific reports of the effects of hordenine in human beings. More detailed discussions of hordenine pharmacology and toxicology are given below this section.
基本信息
中文名称
大麦芽碱
英文名称
hordenine
中文别名
4-羟基-N,N-二甲基苯乙胺、4-(2-二甲基氨基乙基)苯酚、麦芽碱、大麦碱、安哈林、對羥-N,N-二甲苯乙胺、氮位N,N-二甲基对羟基苯乙胺、4-[2-(二甲基氨基)乙基]苯酚
英文别名
4-[2-(Dimethylamino)ethyl]phenol、Cactine、Anhaline、N,N-dimethyltyramine、Hordenin、Phenol, 4-[2-(dimethylamino)ethyl]-、Hordetin、p-[2-(dimethylamino)ethyl]phenol、Hordenine、4-(2-(Dimethylamino)ethyl)phenol、Ordenina、Eremursine、2-(4-Hydroxyphenyl)-N,N-dimethylethylamine (4-(2-Dimethylaminoethyl)phenol、Anhalin、4-Hydroxy-N,N-dimethylphenethylamine、4-[2-(dimethylamino)ethyl]phenol、Anhalin-d6、N,N-dimethyl-2-(4-hydroxyphenyl)ethylamine、Ordenine
CAS号
539-15-1
分子式
C10H15NO
分子量
165.232
精确质量
165.115
PSA
23.47
LOGP
1.4963
编号系统
EINECS号
208-710-4
物化性质
密度
1.026g/cm3
沸点
270.2ºC at 760 mmHg
闪点
123.5ºC
折射率
1.542
安全信息
海关编码
2922199090
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