化合物简介
Epiestriol (INN) (brand names Actriol, Arcagynil, Klimadoral), or epioestriol (BAN), also known as 16β-epiestriol or simply 16-epiestriol as well as 16β-hydroxy-17β-estradiol, is an endogenous, steroidal, weak estrogen, and the 16-epimer of estriol (which is 16α-hydroxy-17β-estradiol). Epiestriol is (or has previously been) used clinically in the treatment of acne. In addition to its estrogenic actions, epiestriol has been found to possess significant anti-inflammatory properties without glycogenic activity or immunosuppressive effects, an interesting finding that is in contrast to conventional anti-inflammatory steroids like hydrocortisone (a glucocorticoid).
基本信息
中文名称
表雌三醇
英文名称
16β-hydroxyestradiol
中文别名
异雌三醇、雌三醇杂质F
英文别名
16beta-hydroxyestradiol、16-Epiestratriol、16-epioestriol、EPIESTRIOL,16、Actriol、16b,17b-Estriol、16-EPISTRIOL、Epioestriol、Epiestriol、Estriol (3,16.β.,17.β.)、16-EPIESTRIOL、Estra-1,3,5(10)-triene-3,16,17-triol, (16β,17β)-
CAS号
547-81-9
分子式
C18H24O3
分子量
288.381
精确质量
288.173
PSA
60.69
LOGP
2.58
编号系统
UNII
8XZ32LI44K
物化性质
密度
1.255g/cm3
沸点
469ºC at 760 mmHg
熔点
289-291ºC
闪点
220.8ºC
折射率
1.624
储存条件
-20ºC Freezer
安全信息
WGK Germany
3