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(15S,5Z,8Z,11Z,13E)-15-羟基二十碳四烯酸

(15S,5Z,8Z,11Z,13E)-15-羟基二十碳四烯酸

CAS号:54845-95-3
英文名:15(S)-HETE
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化合物简介
15-Hydroxyicosatetraenoic acid (also termed 15-HETE, 15(S)-HETE, and 15S-HETE) is an endogenous eicosanoid, i.e. a metabolite of arachidonic acid. Various cell types and tissues first produce 15-Hydroperoxyicosatetraenoic acid (15-HpETE). These initial hydroperoxy products are extremely short lived in cells: if not otherwise metabolized, they are reduced to 15-HETE. Both these molecules are are hormone-like autocrine and paracrine signalling agents, involved in inflammation response, but often are further metabolized to a wide range of products that are much more potent, including eoxins.
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