化合物简介
ML 3403 is a potent and selective p38 mitogen-activated protein kinase (MAPK) inhibitor. MAPK is a key mediator in cytokine-induced signaling events and plays an integral role in disease states including oncogenesis, autoimmune diseases, and inflammatory processes. Therefore, MAPK inhibitors such as ML 3403 provides an attractive strategy for therapeutic intervention.
基本信息
中文名称
ML3403
英文名称
4-[4-(4-Fluorophenyl)-2-(methylsulfanyl)-1H-imidazol-5-yl]-N-(1-p henylethyl)-2-pyridinamine
中文别名
英文别名
p38 MAP inhibitor III
CAS号
549505-65-9
分子式
C23H21FN4S
分子量
404.503
精确质量
404.147
PSA
78.9
LOGP
6.2458
编号系统
MDL号
MFCD09037547
上游原料
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