化合物简介
One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
基本信息
中文名称
L-甲状腺素钠盐五水合物
英文名称
levothyroxine sodium anhydrous
中文别名
左甲状腺素钠、L-甲状腺素钠、L-甲状腺素钠五水合物
英文别名
(S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propionic Acid Sodium Salt Pentahydrate、Levothyroxine sodium
CAS号
55-03-8
分子式
C15H20I4NNaO9
分子量
888.928
精确质量
888.721
PSA
141.76
LOGP
3.6014
编号系统
UNII
054I36CPMN
物化性质
沸点
576.3ºC at 760 mmHg
熔点
207-210 (dec.)(lit.)ºC
闪点
302.3ºC
储存条件
2-8ºC
安全信息
安全说明
S22-S24/25
危险品运输编码
UN 2811
危险类别
6.1(a)
包装等级
II
上游原料
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