化合物简介
Nitazoxanide is a broad-spectrum antiparasitic and broad-spectrum antiviral drug that is used in medicine for the treatment of various helminthic, protozoal, and viral infections. It is indicated for the treatment of infection by Cryptosporidium parvum and Giardia lamblia in immunocompetent individuals and has been repurposed for the treatment of influenza. Nitazoxanide has also been shown to have in vitro antiparasitic activity and clinical treatment efficacy for infections caused by other protozoa and helminths; emerging evidence suggests that it possesses efficacy in treating a number of viral infections as well.
基本信息
中文名称
硝唑尼特
英文名称
[2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl] acetate
中文别名
硝唑克酰胺、邻[N-(5-硝基噻唑-2-基)氨基甲酰]苯酚乙酸酯
英文别名
[14C]-Nitazoxanide、Cryptaz、Nitazoxanide、Heliton、Colufase、Nitazoxanida、NITAZOXANIDE、Alinia、Nitazoxanidum、Daxon、Nitazoxamide
CAS号
55981-09-4
分子式
C12H9N3O5S
分子量
307.282
精确质量
307.026
PSA
142.35
LOGP
2.8251
编号系统
MDL号
MFCD00416599
物化性质
外观与性状
淡黄色至白色结晶粉末
密度
1.532 g/cm3
熔点
202ºC
储存条件
-20ºC Freezer
安全信息
海关编码
2942000000
危险性防范说明
P261; P305 + P351 + P338
危险性描述
H302; H315; H319; H335
信号词
Warning
危险标志
GHS07