化合物简介
77-LH-28-1 is a selective agonist of muscarinic acetylcholine receptor subtype 1 (M1) discovered in 2008. It is an allosteric agonist, exhibiting over 100-fold specificity for M1 over other muscarinic receptor subtypes. 77-LH-28-1 penetrates the brain by crossing the blood brain barrier and is therefore a useful pharmocologic tool with cognition enhancing effects.
基本信息
中文名称
1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
英文名称
1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
中文别名
英文别名
CAS号
560085-11-2
分子式
C21H32N2O
分子量
328.492
精确质量
328.251
PSA
23.55
LOGP
4.261
合成路线