化合物简介
Prosultiamine (Alinamin, Binova, Jubedel, Taketron, Thiobeta, Thiotiamina), also known as thiamine propyl disulfide (TPD), is a disulfide thiamine derivative developed in Japan in the 1950s as a treatment for vitamin B1 deficiency. It has improved lipid solubility relative to thiamine and is not rate-limited by dependency on intestinal transporters for absorption, hence the reasoning for its development. It is also a potential treatment for HTLV, since it has been shown to reduce viral load and symptoms.
基本信息
中文名称
丙舒硫胺
英文名称
Prosultiamine
中文别名
维生素 B1 丙基硫化物、N-[(4-氨基-2-甲基-5-嘧啶基)甲基]-N-(4-羟基-1-甲基-2-丙基二硫丁-1-烯基)甲酰胺、丙硫胺嘧啶
英文别名
nevriton、arinamine、aliton、alinamin、nuvelbiv.c.a.、tipidi、nervilon、thiamine propyldisulfide、neurvita、Alinamine、tiotiamina
CAS号
59-58-5
分子式
C15H24N4O2S2
分子量
356.507
精确质量
356.134
PSA
142.94
LOGP
3.948
编号系统
UNII
UI32MM3XE3
物化性质
外观与性状
白色结晶或结晶粉末
密度
1.261 g/cm3
沸点
593.7ºC at 760 mmHg
闪点
312.9ºC
折射率
1.62
安全信息
安全说明
S26; S36/37/39
危险类别码
R20/21/22
