化合物简介
Gabaculine is a naturally occurring neurotoxin first isolated from the bacteria Streptomyces toyacaensis, which acts as a potent and irreversible GABA transaminase inhibitor, and also a GABA reuptake inhibitor. Gabaculine is also known as 3-amino-2,3-dihydrobenzoic acid hydrochloride and 5-amino cyclohexa-1,3 dienyl carboxylic acid. Gabaculine increased GABA levels in the brain and had an effect on convulsivity in mice.
基本信息
中文名称
3-氨基-2,3-二氢苯甲酸盐酸盐
英文名称
D,L-Gabaculine, Hydrochloride
中文别名
英文别名
5-aminocyclohexa-1,3-diene-1-carboxylic acid,hydrochloride
CAS号
59556-17-1
分子式
C7H10ClNO2
分子量
175.613
精确质量
175.04
PSA
63.32
LOGP
1.7869
编号系统
MDL号
MFCD00036983
物化性质
沸点
304.6ºC at 760 mmHg
熔点
203ºC (dec.)(lit.)
闪点
138ºC
储存条件
2-8ºC
安全信息
安全说明
S22; S24/25
海关编码
2922499990
合成路线
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