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(R)-2-丙基哌啶

(R)-2-丙基哌啶

CAS号：5985-99-9

英文名：(2R)-2-Propylpiperidine

分子式

C8H17N

熔点

密度

分子量

127.227

沸点

溶解度

信号词

危险品标志

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化合物简介

毒芹碱是一个有毒的生物碱，最早在毒参中发现，对人和家畜有神经毒性，作用于外周神经系统，会使人窒息，服用0.2g就有生命危险。古希腊哲学家苏格拉底即死于毒芹碱。毒芹碱化学式为“2-丙基哌啶”，分子式C8H17N，分子量127.23。含有一个手性碳原子，因此有R型和S型两个异构体，两种异构体在毒参中都有发现。它也是第一个被合成的生物碱，在1886由Albert Ladenburg合成。

基本信息

中文名称

(R)-2-丙基哌啶

英文名称

(2R)-2-Propylpiperidine

中文别名

英文别名

Piperidine, 2-propyl-, (R)-

CAS号

5985-99-9

分子式

C8H17N

分子量

127.227

精确质量

127.136

PSA

12.03

LOGP

2.2574

编号系统

UNII

QKK1SI92BR

合成路线

1392047-86-7

(R)-2-丙基哌啶

(R)-2-丙基哌啶

上游原料

共找到77个上游原料 >

2-哌啶甲醇

(R)-1-<(Benzyloxy)carbonyl>-2-propyl-2,3-dihydro-4-pyridone

(R)-1-<(Benzyloxy)carbonyl>-2-propyl-2,3-dihydro-4-pyridone

N-benzyl-N-(but-3-en-1-yl)hepta-2,5-diyn-4-amine

N-benzyl-N-(but-3-en-1-yl)hepta-2,5-diyn-4-amine

(S)-N,N-dibenzyl-8-((triisopropylsilyl)oxy)oct-5-yn-4-amine

(S)-N,N-dibenzyl-8-((triisopropylsilyl)oxy)oct-5-yn-4-amine

benzyl (R)-non-8-en-4-ylcarbamate

benzyl (R)-non-8-en-4-ylcarbamate

2R-(+)-4,5-didehydro-N-[(R)-α-methylbenzyl]-2-propyl-piperidine

2R-(+)-4,5-didehydro-N-[(R)-α-methylbenzyl]-2-propyl-piperidine

上游原料

2-哌啶甲醇 (R)-1-<(Benzyloxy)carbonyl>-2-propyl-2,3-dihydro-4-pyridone N-benzyl-N-(but-3-en-1-yl)hepta-2,5-diyn-4-amine (S)-N,N-dibenzyl-8-((triisopropylsilyl)oxy)oct-5-yn-4-amine 2R-(+)-4,5-didehydro-N-[(R)-α-methylbenzyl]-2-propyl-piperidine (E)-octa-5,7-dien-1-amine 2-丙基哌啶 (2S,3R,5S,8aR)-3-methyl-2-phenyl-5-propylhexahydro-5H-oxazolo[3,2-a]pyridine-5-carbonitrile (R)-(-)-N-Boc-coniine (-)-2-cyano-6-oxazolopiperidine (6R)-6-propylpiperidin-2-one (S)-2-allyl-piperidine-1-carboxylic acid tert-butyl ester benzyl (2S)-2-(hydroxymethyl)piperidine-1-carboxylate methyl 6-oxononanoate (S)-5-(dibenzylamino)oct-3-yn-1-ol (+)-N-[(R)-α-methylbenzyl]-hept-1-ene-4-amine (R)-2-(((R)-1-(1,3-dioxolan-2-yl)heptan-4-yl)(benzyl)amino)-2-phenylethanol 1-((S)-phenyl((R)-2-propylpiperidin-1-yl)methyl)naphthalen-2-ol (S,Z)-benzyl 2-(prop-1-en-1-yl)piperidine-1-carboxylate 4-甲氧基-3-(三异丙基甲硅烷基)嘧啶 (R)-(-)-1-(benzyloxycarbonyl)-1,2,3,4-tetrahydro-2-propylpyridine 4-methoxy-1-((((1R,2S,5R)-5-methyl-2-(2-phenylpropan-2-yl)cyclohexyl)oxy)carbonyl)-3-(triisopropylsilyl)pyridin-1-ium chloride (R)-2-Propyl-1-(((1R,2S,5R)-8-phenylmenthoxy)carbonyl)-5-(triisopropylsilyl)-2,3-dihydro-4-pyridone (1S,2R)-1-phenyl-2-((R)-2-propylpiperidin-1-yl)propan-1-ol (4S,4'R)-3-(8'-chloro-4'-octanamino)-4-phenylmethyl-2-oxazolidinone 1-N-苄氧羰基-2-羟甲基哌啶 1-((S)-((S)-2-allylpiperidin-1-yl)(phenyl)methyl)naphthalen-2-ol (R)-2-((3aS,6R,7aR)-8,8-dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazole-1-carbonyl)-6-propyl-2,3,4,5-tetrahydropyridine 1-oxide (2E,5E)-N-benzyl-N-(but-3-en-1-yl)hepta-2,5-dien-4-amine (2S)-2-allyl-1-[(1R)-2-hydroxy-1-phenylethyl]piperidine (6R,1'S)-(-)-N-(1-phenylbutoxy)-6-non-1-enylamine (R)-1-<(Benzyloxy)carbonyl>-4-chloro-2-propyl-1,2-dihydropyridine delta-戊内酯 5-氧代戊酸甲酯 2,3-pentadienyl bromide (3R,8aR)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine (R)-1-benzyl-2-propylpiperidine (3R,8aS)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo<3,2-a>pyridine octa-5,7-dienenitrile (R,E)-1-benzyl-6-(prop-1-en-1-yl)-1,2,3,6-tetrahydropyridine (R)-2-(2,6-dioxopiperidin-1-yl)-2-phenylethyl acetate (R)-1-benzyloxycarbonyl-2-propyl-1,2,3,6-tetrahydropyridine (R)-(-)-N-Benzylocta-5,6-dienylamine (S)-N-Cbz-piperidine-2-carbaldehyde 1-((3aS,6R,7aR)-8,8-dimethyl-2,2-dioxidotetrahydro-3H-3a,6-methanobenzo[c]isothiazol-1(4H)-yl)-5-(2-propyl-1,3-dioxolan-2-yl)pentan-1-one (4S,2'R)-3-(2'-propyl-piperidin-1-yl)-4-phenylmethyl-2-oxazolidinone (+)-N-allyl,N-[(R)-α-methylbenzyl]-hept-1-ene-4-amine