百科

噻唑呋林

CAS号：60084-10-8

英文名：2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide

分子式

C9H12N2O5S

熔点

密度

1.648g/cm3

分子量

260.267

沸点

641.3ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

Tiazofurin has antitumor activity and is a potential therapeutic agent in the treatment of cancer. Tiazofurin acts as an inhibitor of Inosine-5'-monophosphate (IMP) dehydrogenase.

基本信息

中文名称

噻唑呋林

英文名称

2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide

中文别名

英文别名

Tiazofurine、Tiazofurina、TIAZOFURIN、Tiazofurina [Spanish]、Riboxamide、Tiazofurinum [Latin]、Tiazofurinum、[3H]-Tiazofurin、Tiazole

CAS号

60084-10-8

分子式

C9H12N2O5S

分子量

260.267

精确质量

260.047

PSA

154.14

LOGP

-0.9037

编号系统

UNII

ULJ82834RE

物化性质

密度

1.648g/cm3

沸点

641.3ºC at 760 mmHg

闪点

341.6ºC

折射率

1.674

安全信息

海关编码

2934100090

合成路线

共找到3条合成路线 >

60084-09-5

2-(2,3,5-三-O-苯甲酰基-beta-D-呋喃核糖基)-4-噻唑羧酸乙酯

上游原料

1-cyano-2,3-O-isopropylidene-5-O-benzoyl-β-D-ribofuranose

5517-61-3

methyl 3'-O-benzoyl-β-D-apiofuranoside

477881-06-4

methyl 1'-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)thiazoline-4'-carboxylate

23316-67-8

1-氰基-2,3,5-三苯甲酰氧基-β-D-呋喃核糖

62404-62-0

β-D-ribofuranosyl-1-carboximidic acid methyl ester

4099-85-8

甲基-2,3-O-异亚丙基-beta-D-呋喃核糖苷

下游产品

共找到3个下游商品 >

92952-33-5

2-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide

83285-83-0

噻唑-4-甲酰胺腺嘌呤二核苷酸

92952-40-4

2-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide

上游原料

1-cyano-2,3-O-isopropylidene-5-O-benzoyl-β-D-ribofuranose methyl 3'-O-benzoyl-β-D-apiofuranoside methyl 1'-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)thiazoline-4'-carboxylate 1-氰基-2,3,5-三苯甲酰氧基-β-D-呋喃核糖 β-D-ribofuranosyl-1-carboximidic acid methyl ester 甲基-2,3-O-异亚丙基-beta-D-呋喃核糖苷 (3,4-二苯甲酰氧基-5-硫代氨基甲酰四氢呋喃-2-基)甲基苯甲酸酯 ethyl 5-amino-2-(β-D-ribofuranosyl)thiazole-4-carboxylate ethyl 2-(5'-O-benzoyl-2',3'-O-isopropylidene-β-D-ribofuranosyl)thiazoline-4-carboxylate ethyl 2-(5'-O-benzoyl-2',3'-O-isopropylidene-β-D-ribofuranosyl)thiazole-4-carboxylate methyl 2,5-anhydroallonothioate ethyl 2-(5'-O-benzoyl-β-D-ribofuranosyl)thiazole-4-carboxylate methyl 3'-O-benzoyl-2,3-O-isopropylidene-β-D-apiofuranoside 1-乙酰基-2,3,5-三苯甲酰氧基-1-beta-D-呋喃核糖 (1R,5R)-3-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-4-thia-2,6-diazabicyclo[3.2.0]hept-2-en-7-one 2-beta-D-呋喃核糖基-4-噻唑羧酸乙酯 benzyl 3-methyl-2-[(1R,5R)-3-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-7-oxo-4-thia-2,6-diazabicyclo[3.2.0]hept-2-en-6-yl]but-2-enoate benzyl 3-methyl-2-(2-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)thiazol-4-ylcarbonylamino)but-2-enoate 2-(2,3,5-三-O-苯甲酰基-beta-D-呋喃核糖基)-4-噻唑羧酸乙酯

下游产品

2-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide 噻唑-4-甲酰胺腺嘌呤二核苷酸 2-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide