化合物简介
Adapromine is an antiviral drug of the adamantane group related to amantadine (1-aminoadamantane), rimantadine (1-(1-aminoethyl)adamantane), and memantine (1-amino-3,5-dimethyladamantane) that is marketed in Russia for the treatment and prevention of influenza. It is an alkyl analogue of rimantadine and is similar to rimantadine in its antiviral activity but possesses a broader spectrum of action, being effective against influenza viruses of both type A and B. Strains of type A influenza virus with resistance to adapromine and rimantadine and the related drug deitiforine were encountered in Mongolia and the Soviet Union in the 1980s.
基本信息
中文名称
1-金刚烷-1-基-丙胺
英文名称
1-(1-Adamantyl)propan-1-amine
中文别名
英文别名
Adapromine、1-Adamantan-1-yl-propylamine、1-adamantanylpropylamine
CAS号
60196-90-9
分子式
C13H23N
分子量
193.328
精确质量
193.183
PSA
26.02
LOGP
3.6404
编号系统
MDL号
MFCD01838799
物化性质
沸点
262.3ºC at 760 mmHg
闪点
108.3ºC
安全信息
海关编码
2921300090