化合物简介
Binedaline (Ixprim), also called binodaline, is a drug that was being investigated as an antidepressant in the 1980s but never marketed. It acts as a selective norepinephrine reuptake inhibitor (Ki = 25 nM), with relatively insignificant influence on the serotonin (Ki = 847 nM) and dopamine (Ki >= 2 µM) transporters. It has negligible affinity for the α-adrenergic, mACh, H1, or 5-HT2 receptors.
基本信息
中文名称
苯奈达林
英文名称
N,N,N'-trimethyl-N'-(3-phenylindol-1-yl)ethane-1,2-diamine
中文别名
N-(2-(二甲基氨基)乙基)-N-甲基-3-苯基-1H-吲哚-1-胺
英文别名
Binodalina、Binodaline、Binodalina [INN-Spanish]、1-[[2-(dimethylamino)ethyl]methyl]amino-3-phenylindole、Binedalina [INN-Spanish]、Binedaline、Binedalinum [Latin]、Sgd scha 1509 (siegfried)、Binedalina [Spanish]、Binedalinum [INN-Latin]、Binodalinum [INN-Latin]
CAS号
60662-16-0
分子式
C19H23N3
分子量
293.406
精确质量
293.189
PSA
11.41
LOGP
3.4377
编号系统
UNII
3AVG9P140R
物化性质
密度
1.03g/cm3
沸点
441.2ºC at 760 mmHg
闪点
220.6ºC
折射率
1.577
安全信息
海关编码
2933990090
危险品运输编码
UN 3249
危险类别
6.1(b)
包装等级
III