化合物简介
Delanterone (INN) (developmental code name GBR-21162), also known as 1α-methylandrosta-4,16-dien-3-one, is a steroidal antiandrogen described as an anti-acne agent which was never marketed. The compound showed poor efficacy as an antiandrogen in vivo in animals, suggestive of low activity or a short half-life, and likely in relation to this was not further developed. It was characterized and reported on in 1977.
基本信息
中文名称
地仑雄酮
英文名称
Delanterone
中文别名
英文别名
(1|A,5|A,17|A)-1-methyl-3-oxoandrostan-17-yl acetate
CAS号
63014-96-0
分子式
C20H28O
分子量
284.436
精确质量
284.214
PSA
17.07
LOGP
4.9304
编号系统
UNII
AM2KZ47R0J
物化性质
密度
1.05g/cm3
沸点
397.8ºC at 760 mmHg
闪点
186.1ºC
折射率
1.552