化合物简介
Asunaprevir (formerly BMS-650032, brand name in Japan and Russia Sunvepra) is an experimental drug candidate for the treatment of hepatitis C. It is undergoing development by Bristol-Myers Squibb and is currently in Phase III clinical trials.
基本信息
中文名称
Asunaprevir; (1R,2S)-N-[(1,1-二甲基乙氧基)羰基]-3-甲基-L-缬氨酰-(4R)-4-[(7-氯-4-甲氧基-1-异喹啉基)氧基]-L-脯氨酰-1-氨基-N-(环丙基磺酰基)-2-乙烯基环丙基甲酰胺
英文名称
tert-butyl N-[(2S)-1-[(2S,4R)-4-(7-chloro-4-methoxyisoquinolin-1-yl)oxy-2-[[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
中文别名
英文别名
Asunaprevir (JAN/USAN)、N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-4-((7-chloro-4-methoxy-1-isoquinolinyl)oxy)-N-((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-L-prolinamide、CS-0674、Asunaprevir、tert-butyl (S)-1-((2S,4R)-4-(7-chloro-4-methoxyisoquinolin-1-yloxy)-2-((1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-vinylcyclopropylcarbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-ylcarbamate
CAS号
630420-16-5
分子式
C35H46ClN5O9S
分子量
748.286
精确质量
747.27
PSA
201.18
LOGP
6.7575
编号系统
UNII
S9X0KRJ00S
合成路线
上游原料
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