化合物简介
Dimethoxy-4-amylamphetamine (DOAM) is a lesser-known psychedelic drug and a substituted amphetamine. DOAM was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), the minimum dosage is listed as 10mg, and the duration is unknown. DOAM produces a bare threshold and tenseness. As the 4-alkyl chain length is increased from shorter homologues such as DOM, DOET and DOPR which are all potent hallucinogens, the 5-HT2 binding affinity increases, rising to a maximum with the 4-(n-hexyl) derivative before falling again with even longer chains, but compounds with chain length longer than n-propyl, or with other bulky groups such as isopropyl, t-butyl or γ-phenylpropyl at the 4- position, fail to substitute for hallucinogens in animals or produce hallucinogenic effects in humans, suggesting these have low efficacy and are thus antagonists or weak partial agonists at the 5-HT2A receptor.
基本信息
中文名称
1-(2,5-dimethoxy-4-pentylphenyl)propan-2-amine
英文名称
1-(2,5-dimethoxy-4-pentylphenyl)propan-2-amine
中文别名
英文别名
2,5-Dimethoxy-4-amylamphetamine
CAS号
63779-90-8
分子式
C16H27NO2
分子量
265.391
精确质量
265.204
PSA
44.48
LOGP
4.0265
安全信息
海关编码
2922199090
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