化合物简介
2-(3-Phenyl-4,5-dihydroisoxazol-5-yl)acetic Acid reduces the secretion of IL-1β, TNF-α and IL-10 from purified murine macrophages but not of T cells; and reduces the activation of NF-κB and p38 MAP kinase pathways along with up-regulation of ERK pathways. 2-(3-Phenyl-4,5-dihydroisoxazol-5-yl)acetic Acid inhibits proliferation of enterobacterial antigen-reactive CD4+CD25- T cells in vitro .
基本信息
中文名称
3-苯基-2-异恶唑啉-5-乙酸
英文名称
2-(3-phenyl-4,5-dihydro-1,2-oxazol-5-yl)acetic acid
中文别名
英文别名
3-phenyl-4,5-dihydro-5-isoxazoleacetic acid、4,5-DIHYDRO-3-PHENYL-5-ISOXAZOLEACETIC ACID、GIT 27
CAS号
6501-72-0
分子式
C11H11NO3
分子量
205.21
精确质量
205.074
PSA
58.89
LOGP
1.0899
