化合物简介
17α-Dihydroequilin, or α-dihydroequilin, also known as estra-1,3,5(10),7-tetraene-3,17α-diol, is a natural estrogen found in horses that is closely related to equilin and equilenin. The compound, as the sodium salt of its sulfate ester, is present in the pharmaceutical drug Premarin, a conjugated estrogenic extract of the urine of pregnant mares, and is the third highest quantity constituent in the formulation (13.8%).
基本信息
中文名称
17α-二氢马烯雌酮
英文名称
17α-Dihydroequilin
中文别名
17α-二氢马烯雌甾酮
英文别名
7-Dehydro-17α-estradiol、Estra-1,3,5(10),7-tetraen-3,17α-diol、(9S,13S,14S,17R)-13-methyl-6,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthrene-3,17-diol、α-dihydroequilin、α-Equilol、Estra-1,3,5(10),7-tetraene-3,17-diol, (17α)-、(17α)-Estra-1,3,5(10),7-tetraene-3,17-diol
CAS号
651-55-8
分子式
C18H22O2
分子量
270.366
精确质量
270.162
PSA
40.46
LOGP
3.5293
编号系统
UNII
48P73794OJ
物化性质
密度
1.23g/cm3
沸点
457.798ºC at 760 mmHg
闪点
217.155ºC
折射率
1.637
上游原料
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