化合物简介
Fenretinide (4-hydroxy(phenyl)retinamide; 4-HPR) (INN) is a synthetic retinoid derivative. Retinoids are substances related to vitamin A. It has been investigated for potential use in the treatment of cancer, as well as in the treatment of cystic fibrosis, rheumatoid arthritis, acne, psoriasis, and has been found to also slow the production and accumulation of a toxin that leads to vision loss in Stargardt's patients.
基本信息
中文名称
维甲酰酚胺
英文名称
4-hydroxyphenyl retinamide
中文别名
酚维A胺、维甲酸对羟基苯胺、芬维A胺、全反式-N-(4-羟苯基)维甲酸
英文别名
Fenretinide(4-HPR)
CAS号
65646-68-6
分子式
C26H33NO2
分子量
391.546
精确质量
391.251
PSA
49.33
LOGP
6.9353
编号系统
UNII
187EJ7QEXL
物化性质
外观与性状
黄色粉末
密度
1.081 g/cm3
沸点
597.6ºC at 760 mmHg
熔点
162-163°C
闪点
315.2ºC
折射率
1.607
稳定性
Light Sensitive - Protect from Light Exposure
储存条件
-20ºC
安全信息
RTECS号
VH6420000
安全说明
S53-S26-S36/37/39-S45
WGK Germany
3
危险类别码
R60; R61; R20/21/22; R36/37/38
危险品标志
T
危险标志
GHS07, GHS08
信号词
Danger
危险性描述
H302 + H312 + H332; H315; H319; H335; H360
危险性防范说明
P201; P261; P280; P305 + P351 + P338; P308 + P313
