化合物简介
Psoralen (also called psoralene) is the parent compound in a family of natural products known as furocoumarins. It is structurally related to coumarin by the addition of a fused furan ring, and may be considered as a derivative of umbelliferone. Psoralen occurs naturally in the seeds of Psoralea corylifolia, as well as in the common fig, celery, parsley, West Indian satinwood and in all citrus fruits. It is widely used in PUVA (psoralen + UVA) treatment for psoriasis, eczema, vitiligo, and cutaneous T-cell lymphoma. Many furocoumarins are extremely toxic to fish, and some are deposited in streams in Indonesia to catch fish.
基本信息
中文名称
补骨脂素
英文名称
Psoralen
中文别名
补骨内酯、补骨脂提取物、补骨脂、补骨脂内酯、补骨酯、制斑素、线形呋喃香豆素
英文别名
7H-furo[3,2-g][1]benzopyran-7-one、Psoralene、7H-furo[3,2-g]chromen-7-one、6,7-Furanocoumarin、Psorline-P、FICUSIN、Furocoumarin (Psoralen)、Prosuler
CAS号
66-97-7
分子式
C11H6O3
分子量
186.164
精确质量
186.032
PSA
43.35
LOGP
2.5392
编号系统
MDL号
MFCD00010520
EINECS号
200-639-7
物化性质
外观与性状
结晶固体
密度
1.389 g/cm3
沸点
362.6ºC at 760 mmHg
熔点
160-162°C
闪点
173.1ºC
折射率
1.667
储存条件
2-8ºC
安全信息
RTECS号
LV0944000
安全说明
S26
WGK Germany
3
危险类别码
R36/37/38
危险品标志
Xn
危险标志
GHS07
危险性防范说明
P261; P305 + P351 + P338
信号词
Warning
危险性描述
H302; H315; H319; H335
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