化合物简介
Boc-3,5-dihydroxy-1-adamantyl-L-glycine is a reactant in the synthesis of of Saxagliptin, a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
基本信息
中文名称
(2S)-2-[(3R,5S)-3,5-dihydroxy-1-adamantyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetic acid
英文名称
(2S)-2-[(3R,5S)-3,5-dihydroxy-1-adamantyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetic acid
中文别名
英文别名
TRI048
CAS号
681282-72-4
分子式
C17H27NO6
分子量
341.399
精确质量
341.184
PSA
119.58
LOGP
1.6149
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