化合物简介
Afimoxifene, also known as 4-hydroxytamoxifen (4-OHT, 4-HT, OHTAM, others), is a selective estrogen receptor modulator which is the active metabolite of tamoxifen. Afimoxifene is a transdermal gel formulation and is being developed by Ascend Therapeutics, Inc. under the trademark TamoGel.
基本信息
中文名称
4-羟基他莫西芬
英文名称
Afimoxifene
中文别名
阿非昔芬
英文别名
Propiophenone,4\'-[2-(diethylamino)ethoxy]-,hydrochloride、1-[4-(2-Diaethylamino-aethoxy)-phenyl]-propan-1-on,Hydrochlorid、1-[4-(2-diethylaminoethyloxy)phenyl]propan-1-one hydrochloride、4-hydroxytamoxifene、1-[4-(2-dimethylaminoethoxy)phenyl]-1-(4-hydroxyphenyl)-2-phenylbut-1-ene、(E,Z)-4-hydroxytamoxifen、1-[4-(2-diethylamino-ethoxy)-phenyl]-propan-1-one,hydrochloride
CAS号
68392-35-8
分子式
C26H29NO2
分子量
387.514
精确质量
387.22
PSA
32.7
LOGP
5.7017
编号系统
UNII
17197F0KYM
物化性质
密度
1.092
安全信息
危险标志
GHS07, GHS08
危险性描述
H302; H312; H332; H361
信号词
Warning
危险性防范说明
P280
