百科

N2-异丁酰基-2′-脱氧鸟苷

CAS号：68892-42-2

英文名：N2-Isobutyryl-2'-deoxyguanosine

分子式

C14H19N5O5

熔点

≥300°C

密度

1.72 g/cm3

分子量

337.331

沸点

溶解度

信号词

危险品标志

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化合物简介

2'-Deoxy-N-(2-methyl-1-oxopropyl)-guanosine is used to prepare methylene carboxamide-linked dinucleotides as HIV-1 nucleocapsid protein NCp7 inhibitors.

基本信息

中文名称

N2-异丁酰基-2′-脱氧鸟苷

英文名称

N2-Isobutyryl-2'-deoxyguanosine

中文别名

N2-异丁酰基-2\'-脱氧鸟甙、N2-异丁酰-2\'-脱氧鸟甙、N2-异丁酰-2\'-脱氧鸟苷、N2-异丁酰-2’-脱氧鸟苷

英文别名

N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide

CAS号

68892-42-2

分子式

C14H19N5O5

分子量

337.331

精确质量

337.139

PSA

142.36

LOGP

-0.5722

编号系统

MDL号

MFCD00010060

PubChem号

24881143

BRN号

4561317

物化性质

外观与性状

白色至灰白色粉末

密度

1.72 g/cm3

熔点

≥300°C

储存条件

-20ºC

安全信息

安全说明

S22-S24/25

WGK Germany

海关编码

2934999090

合成路线

共找到4条合成路线 >

75759-63-6

5'-O-dimethoxytrityl-N2-isobutyroyl-2'-deoxyguanosine

上游原料

N2-异丁酰-5'-O-(4,4'-二甲氧基三苯基)-2'-脱氧鸟苷

82921-54-8

N-(9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-(2-((4-nitrophenyl)thio)ethoxy)-9H-purin-2-yl)isobutyramide

82921-59-3

3',5'-bis-O-[(tert-butyl)dimethylsilyl]-O6-(2-cyanoethyl)-2'-deoxy-N2-isobutyrylguanosine

5'-O-dimethoxytrityl-N2-isobutyroyl-2'-deoxyguanosine

下游产品

共找到4个下游商品 >

68892-41-1

N2-异丁酰-5'-O-(4,4'-二甲氧基三苯基)-2'-脱氧鸟苷

82921-57-1

N-[9-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-[2-(4-nitrophenyl)ethoxy]purin-2-yl]-2-methylpropanamide

上游原料

N2-异丁酰-5'-O-(4,4'-二甲氧基三苯基)-2'-脱氧鸟苷 N-(9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-(2-((4-nitrophenyl)thio)ethoxy)-9H-purin-2-yl)isobutyramide 3',5'-bis-O-[(tert-butyl)dimethylsilyl]-O6-(2-cyanoethyl)-2'-deoxy-N2-isobutyrylguanosine 异丁酸酐异丁酰氯 5'-O-dimethoxytrityl-N2-isobutyroyl-2'-deoxyguanosine N-isobutyroyldeoxyguanosine 5'-(3'',5''-dimethoxybenzoin)carbonate 3',5'-bis-O-[(tert-butyl)dimethylsilyl]-2'-deoxy-N2-isobutyryl-O6-[2-(4-nitrophenyl)ethyl]guanosine 2-N-isobutyryl-6-O-(cyanoethyl)-2'-deoxyguanosine 2'-deoxy-N2-isobutyrylguanosine 3',5'-diisobutyrate N-[9-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-[2-(4-nitrophenyl)ethoxy]purin-2-yl]-2-methylpropanamide 2'-脱氧鸟苷水合物 3',5'-bis-O-[(tert-butyl)dimethylsilyl]-2'-deoxy-N2-isobutyryl-O6-[(2,4,6-triisopropylphenyl)sulfonyl]guanosine 2-N-3',5'-O-triisobutyryl-6-O-(2,4,6-triisopropylbenzenesulfonyl)-2'-deoxyguanosine N2-异丁酰基鸟苷一水合物鸟苷异戊酸酐 N-isobutyryl-3',5'-di-O-levulinyl-2'-deoxyguanosine N2-isobutyryl-2'-O-p-toluenesulfonylguanosine 9-[3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-ribofuranosyl]-N2-isobutyrylguanine N2-isobutyryl-2'-O-p-toluenesulfonyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanyl)guanosine 3',5'-bis-O-trimethylsilyl-2'-deoxyguanosine

下游产品

N2-异丁酰-5'-O-(4,4'-二甲氧基三苯基)-2'-脱氧鸟苷 N-[9-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-[2-(4-nitrophenyl)ethoxy]purin-2-yl]-2-methylpropanamide 2'-脱氧鸟苷水合物 2'-脱氧鸟苷3',5'-二磷酸酯