化合物简介
Etilefrine is a cardiac stimulant used as an antihypotensive. It is a sympathomimetic amine of the 3-hydroxy-phenylethanolamine series used in treating orthostatic hypotension of neurological, cardiovascular, endocrine or metabolic origin. Intravenous infusion of this compound increases cardiac output, stroke volume, venous return and blood pressure in man and experimental animals, suggesting stimulation of both α and β adrenergic receptors. However, in vitro studies indicate that etilefrine has a much higher affinity for β1 (cardiac) than for β2 adrenoreceptors.
基本信息
中文名称
乙苯福林
英文名称
3-[2-(Ethylamino)-1-hydroxyethyl]phenol
中文别名
英文别名
ethylphenylarsine chloride、Aethyl-chlor-phenyl-arsin、Arsine,chloroethylphenyl-(6CI,7CI,8CI)、Arsinous chloride,ethylphenyl、Aethyl-phenyl-dithiocarbamidsaeure,Ammonium-Salz、ethylphenylephrine、ethyl(phenyl)arsinous chloride、Aethylphenylarsinchlorid、Aethylphenylarsenchlorid、ethyl-chloro-phenyl-arsine、ammonium N-ethyl-N-phenyldithiocarbamate、(RS)-etilefrine、Chloroethylphenylarsine、2-ethylamino-1-(3-hydroxy-phenyl)-ethanol、ethyl-phenyl-dithiocarbamic acid,ammonium salt、[3H]-(+/-)-Etilefrine、Aethyl-phenyl-chlor-arsin、Ethylphenylchloroarsine
CAS号
709-55-7
分子式
C10H15NO2
分子量
181.232
精确质量
181.11
PSA
52.49
LOGP
1.426
编号系统
UNII
ZB6F8MY53V
物化性质
密度
1.127 g/cm3
沸点
351.7ºC at 760 mmHg
闪点
155.5ºC
折射率
1.561
安全信息
海关编码
2922509090