化合物简介
Perafensine (INN) (code name HR-459) is a drug which was investigated as an antidepressant but was never marketed. It has been reported to antagonize the effects of reserpine and to inhibit the reuptake of norepinephrine (norepinephrine reuptake inhibitor); whether it also affects the reuptake of serotonin or dopamine is unclear.
基本信息
中文名称
哌芬新
英文名称
1-phenyl-3-piperazin-1-ylisoquinoline
中文别名
英文别名
1-Phenyl-3-(1-piperazinyl)isoquinoline、1-phenyl-3-piperazin-1-yl-isoquinoline、1-Phenyl-3-piperazinoisoquinoline、3-piperazino-1-phenyl-isoquinoline、Perafensine [INN]、UNII-WU6989IN6X、Perafensine
CAS号
72444-62-3
分子式
C19H19N3
分子量
289.374
精确质量
289.158
PSA
28.16
LOGP
3.7052
编号系统
UNII
WU6989IN6X
物化性质
密度
1.155g/cm3
沸点
503.6ºC at 760 mmHg
闪点
258.4ºC
折射率
1.641
