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氯碳头孢

氯碳头孢

CAS号：76470-66-1

英文名：loracarbef

分子式

C16H16ClN3O4

熔点

密度

1.52g/cm3

分子量

349.769

沸点

662.2ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

Loracarbef is an antibiotic. It is a carbacephem, but it is sometimes grouped together with the second-generation cephalosporin antibiotics. Loracarbef is a synthetic \"carba\" analog of cefaclor, and is more stable chemically.

基本信息

中文名称

氯碳头孢

英文名称

loracarbef

中文别名

英文别名

(6R,7S)-1,3,10-bisabolatriene、(-)-(4S,7S)-zingiberene、5-(1,5-dimethyl-4-hexenyl)-2-methyl-1,3-cyclohexadiene、(6R,7S)-7-[(R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-carboxylic acid、(6R,7S)-zingiberene、(6R,7S)-7-((R)-2-amino-2-phenylacetamido)-3-chloro-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CAS号

76470-66-1

分子式

C16H16ClN3O4

分子量

349.769

精确质量

349.083

PSA

112.73

LOGP

1.7399

编号系统

UNII

W72I5ZT78Z

物化性质

密度

1.52g/cm3

沸点

662.2ºC at 760 mmHg

闪点

354.3ºC

折射率

1.677

合成路线

(R)-氨基苯乙酸甲酯

(R)-氨基苯乙酸甲酯

(6R,7S)-7-氨基-3-氯-8-氧代-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸

(6R,7S)-7-氨基-3-氯-8-氧代-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸

氯碳头孢

上游原料

共找到16个上游原料 >

cis-4-oxo-3-[(phenoxyacetyl)amino]-2-azetidinepropanoic acid

cis-4-oxo-3-[(phenoxyacetyl)amino]-2-azetidinepropanoic acid

cis-β,4-dioxo-3-[(phenoxyacetyl)amino]-2-azetidinepentanoic acid, (4-nitrophenyl)methyl ester

cis-β,4-dioxo-3-[(phenoxyacetyl)amino]-2-azetidinepentanoic acid, (4-nitrophenyl)methyl ester

p-nitrobenzyl 7β-[(phenoxyacetyl)amino]-3-hydroxy-1-carba-1-dethia-3-cephem-4-carboxylate

p-nitrobenzyl 7β-[(phenoxyacetyl)amino]-3-hydroxy-1-carba-1-dethia-3-cephem-4-carboxylate

3-[((R)-carboxy-phenyl-methyl)-amino]-but-2-enoic acid methyl ester

3-[((R)-carboxy-phenyl-methyl)-amino]-but-2-enoic acid methyl ester

p-Nitrobenzyliden-2-aminopyrimidin

p-Nitrobenzyliden-2-aminopyrimidin

N-((2R,3S)-2-(2-(furan-2-yl)ethyl)-4-oxoazetidin-3-yl)-2-phenoxyacetamide

N-((2R,3S)-2-(2-(furan-2-yl)ethyl)-4-oxoazetidin-3-yl)-2-phenoxyacetamide

上游原料

cis-4-oxo-3-[(phenoxyacetyl)amino]-2-azetidinepropanoic acid cis-β,4-dioxo-3-[(phenoxyacetyl)amino]-2-azetidinepentanoic acid, (4-nitrophenyl)methyl ester p-nitrobenzyl 7β-[(phenoxyacetyl)amino]-3-hydroxy-1-carba-1-dethia-3-cephem-4-carboxylate 3-[((R)-carboxy-phenyl-methyl)-amino]-but-2-enoic acid methyl ester p-Nitrobenzyliden-2-aminopyrimidin N-((2R,3S)-2-(2-(furan-2-yl)ethyl)-4-oxoazetidin-3-yl)-2-phenoxyacetamide (6R*,7S*)-3-chloro-7-phenylacetamido-8-oxo-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid tert-butyl (6R,7S)-7-(1,3-dioxoisoindolin-2-yl)-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (6R*,7S*)-3-chloro-7-phthalylimido-8-oxo-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid tert-butyl (6R*,7S*)-3-chloro-7-phthalylimido-8-oxo-1-azabicyclo<4.2.0>oct-2-en-2-carboxylate (6R,7S)-4-nitrobenzyl 3-chloro-7-((R)-2-((4-methoxy-4-oxobut-2-en-2-yl)amino)-2-phenylacetamido)-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate carbacephalosporin hydrochloride 1-benzyl-3β-((S)-2-oxo-4-phenyloxazolidin-3-yl)-4β-[2-(2-furyl)ethyl]azetidin-2-one cis-α-diazo-β,4-dioxo-3-[(phenoxyacetyl)amino]-2-azetidinepentanoic acid,(4-nitrophenyl)methyl ester (R)-氨基苯乙酸甲酯 (6R,7S)-7-氨基-3-氯-8-氧代-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸