百科

ethyl {4-amino-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}acetate

ethyl {4-amino-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}acetate

CAS号：770719-11-4

英文名：ethyl {4-amino-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}acetate

分子式：C17H14ClFN2O3

分子量：348.756

上游原料

1,1-dimethylethyl ethyl {3-[(3-chloro-5-cyanophenyl)oxy]-2-fluoro-4-nitrophenyl} propanedioate

1,1-dimethylethyl ethyl {3-[(3-chloro-5-cyanophenyl)oxy]-2-fluoro-4-nitrophenyl} propanedioate

上游原料

1,1-dimethylethyl ethyl {3-[(3-chloro-5-cyanophenyl)oxy]-2-fluoro-4-nitrophenyl} propanedioate

下游产品

3-chloro-5-[(6-chloro-3-{[5-(2,5-dichloro-4-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 3-chloro-5-[(6-chloro-3-{[5-(3,5-dimethyl-1-{[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]methyl}-1H-pyrazol-4-yl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 3-chloro-5-[(6-chloro-2-fluoro-3-{[5-(2-methyl-3-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}phenyl)oxy]benzonitrile 3-chloro-5-(6-chloro-3-((5-(5-chloro-1-(2-chlorobenzyl)-3-methyl-1H-pyrazol-4-yl)-1,3,4-oxadiazol-2-yl)methyl)-2-fluorophenoxy)benzonitrile N'-({4-chloro-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}acetyl)-5-methyl-2-({[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]methyl}oxy)-4-pyridinecarbohydrazide 3-chloro-5-[(6-chloro-2-fluoro-3-{[5-(4-hydroxy-2-methylphenyl)-1,3,4-oxadiazol-2-yl]methyl}phenyl)oxy]benzonitrile 3-chloro-5-(6-chloro-2-fluoro-3-((5-(4-methyl-2-(pyridin-4-yl)-1H-imidazol-5-yl)-1,3,4-oxadiazol-2-yl)methyl)phenoxy)benzonitrile N'-({4-chloro-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}acetyl)-2-{[(2S)-2,3-dihydroxy-3-methylbutyl]oxy}-5-methyl-4-pyridinecarbohydrazide 3-chloro-5-[(6-chloro-3-{[5-(6-{[(2S)-2,3-dihydroxy-3-methylbutyl]oxy}-2-methyl-3-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 3-[(6-bromo-3-{[5-(3-chloro-1-oxido-4-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]-5-chlorobenzonitrile 2-[(3-chloro-5-cyanophenyl)oxy]-4-{[5-(3-chloro-4-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-3-fluorobenzonitrile 3-chloro-5-(6-chloro-2-fluoro-3-((5-(3-methyl-1H-pyrrol-2-yl)-1,3,4-oxadiazol-2-yl)methyl)phenoxy)benzonitrile 3-chloro-5-[(6-chloro-3-{[5-(6-{[(2S)-2,3-dihydroxy-3-methylbutyl]oxy}-4-methyl-3-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 3-chloro-5-[(6-chloro-3-{[5-(3,5-dimethyl-1H-pyrrol-2-yl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 3-chloro-5-[(6-chloro-2-fluoro-3-{[5-(4-{[3-hydroxy-2-(hydroxymethyl)propyl]oxy}phenyl)-1,3,4-oxadiazol-2-yl]methyl}phenyl)oxy]benzonitrile 3-({6-bromo-2-fluoro-3-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]phenyl}oxy)-5-chlorobenzonitrile 3-chloro-5-(6-chloro-3-((5-(4-chloro-2-ethyl-1H-imidazol-5-yl)-1,3,4-oxadiazol-2-yl)methyl)-2-fluorophenoxy)benzonitrile 3-chloro-5-(6-chloro-3-((5-(3,4-dichlorofuran-2-yl)-1,3,4-oxadiazol-2-yl)methyl)-2-fluorophenoxy)benzonitrile N'-({4-chloro-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}acetyl)-4-methyl-2-(methylsulfonyl)-1H-imidazole-5-carbohydrazide 3-chloro-5-[(6-chloro-3-{[5-(2-chloro-4-methyl-1,3-thiazol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 3-chloro-5-[(6-chloro-2-fluoro-3-{[5-(1-methyl-1H-imidazol-2-yl)-1,3,4-oxadiazol-2-yl]methyl}phenyl)oxy]benzonitrile 3-chloro-5-[(6-chloro-3-{[5-(cyanomethyl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 3-chloro-5-[(6-chloro-2-fluoro-3-{[5-(5-methyl-2-{[2-(methylsulfonyl)ethyl]amino}-4-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}phenyl)oxy]benzonitrile 3-chloro-5-{[6-chloro-3-({[5-chloro-2-(methylthio)-4-pyridinyl]-1,3,4-oxadiazol-2-yl}methyl)-2-fluorophenyl]oxy}benzonitrile 3-chloro-5-[(6-chloro-2-fluoro-3-{[5-(4-methyl-1H-imidazol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}phenyl)oxy]benzonitrile 3-chloro-5-{[6-chloro-2-fluoro-3-({5-[4-methyl-2-(methylsulfonyl)-1H-imidazol- 5-yl]-1,3,4-oxadiazol-2-yl}methyl)phenyl]oxy}benzonitrile 3-chloro-5-[(6-chloro-2-fluoro-3-{[5-(4-methyl-1H-pyrazol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}phenyl)oxy]benzonitrile 3-chloro-5-{[6-chloro-2-fluoro-3-({5-[2-methyl-4-(methyloxy)phenyl]-1,3,4-oxadiazol-2-yl}methyl)phenyl]oxy}benzonitrile 3-[(3-{[5-(3-amino-5-methyl-1H-pyrazol-4-yl)-1,3,4-oxadiazol-2-yl]methyl}-6-chloro-2-fluorophenyl)oxy]-5-chlorobenzonitrile 3-chloro-5-[(6-chloro-3-{[5-(1,4-dimethyl-1H-imidazol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 3-chloro-5-{[6-chloro-2-fluoro-3-({5-[5-methyl-2-({[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]methyl}oxy)-4-pyridinyl]-1,3,4-oxadiazol-2-yl}methyl)phenyl]oxy}benzonitrile 2-{4-chloro-3-[(3-chloro-5-cyanophenyl)oxy]-2- fluorophenyl}acetohydrazide 3-[(6-bromo-3-{[5-(3-chloro-4-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]-5-chlorobenzonitrile 3-chloro-5-({6-chloro-3-[(5-{3,5-dimethyl-1-[2-(methylsulfonyl)ethyl]-1H-pyrazol-4-yl}-1,3,4-oxadiazol-2-yl)methyl]-2-fluorophenyl}oxy)benzonitrile 3-chloro-5-[(6-chloro-3-{[5-(2-{[(2S)-2,3-dihydroxy-3-methylbutyl]oxy}-5-methyl-4-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 3-chloro-5-({6-chloro-3-[(5-{1-[(2S)-2,3-dihydroxy-3-methylbutyl]-3,5-dimethyl-1H-pyrazol-4-yl}-1,3,4-oxadiazol-2-yl)methyl]-2-fluorophenyl}oxy)benzonitrile N'-({4-chloro-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}acetyl)-4-methyl-1H-pyrazole-5-carbohydrazide 3-chloro-5-{[6-chloro-2-fluoro-3-({5-[4-methyl-6-({[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]methyl}oxy)-3-pyridinyl]-1,3,4-oxadiazol-2-yl}methyl)phenyl]oxy}benzonitrile 3-chloro-5-[(3-{[5-(3-chloro-4-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-6-ethenyl-2-fluorophenyl)oxy]benzonitrile 3-chloro-5-{[6-chloro-2-fluoro-3-({5-[2-methyl-6-({[(4S)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]methyl}oxy)-3-pyridinyl]-1,3,4-oxadiazol-2-yl}methyl)phenyl]oxy}benzonitrile 3-chloro-5-[(6-chloro-3-{[5-(4-{[(2S)-2,3-dihydroxy-3-methylbutyl]oxy}phenyl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 3-chloro-5-[(6-chloro-3-{[5-(4-{[(2,2-dimethyl-1,3-dioxan-5-yl)methyl]oxy}phenyl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 2-[(3-chloro-5-cyanophenyl)oxy]-3-fluoro-4-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]benzonitrile 3-chloro-5-[(6-chloro-2-fluoro-3-{[5-(4-methyl-2-oxo-2,3-dihydro-1,3-thiazol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}phenyl)oxy]benzonitrile 3-chloro-5-[(6-chloro-3-{[5-(1,4-dimethyl-1H-pyrazol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 3-chloro-5-[(6-chloro-2-fluoro-3-{[5-(4-methyl-2-{[2-(methylsulfonyl)ethyl]amino}-1,3-thiazol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}phenyl)oxy]benzonitrile 2-{4-bromo-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}acetohydrazide N'-({4-chloro-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}acetyl)-4-methyl-1H-imidazole-5-carbohydrazide 3-chloro-5-[(6-chloro-2-fluoro-3-{[5-(2-fluoro-5-methyl-4-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}phenyl)oxy]benzonitrile