[(8S,10S,11S,13S,14S,16S)-9-氟-11-羟基-10,13,16-三甲基-17-甲硫基羰基-3-氧代-6,7,8,11,12,14,15,16-八氢环戊烯并[a]菲-17-基]乙酸酯_CAS号:79578-14-6

基本信息

中文名称

[(8S,10S,11S,13S,14S,16S)-9-氟-11-羟基-10,13,16-三甲基-17-甲硫基羰基-3-氧代-6,7,8,11,12,14,15,16-八氢环戊烯并[a]菲-17-基]乙酸酯

英文名称

(11β,16β,17α)-9-Fluoro-11-hydroxy-16-methyl-17-[(methylsulfanyl)c arbonyl]-3-oxoandrosta-1,4-dien-17-yl acetate

中文别名

英文别名

Flarex、UNII-9I50C3I3OK、Fluorometholone 17-acetate、9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 17-acetate、FLUOROMETHOLONE ACETATE、Oxylone acetate

CAS号

79578-14-6

分子式

C24H31FO5S

分子量

450.563

精确质量

450.188

PSA

105.97

LOGP

3.7947

编号系统

UNII

LGO8R495QW

物化性质

密度

1.285g/cm3

沸点

557.373ºC at 760 mmHg

闪点

290.889ºC

折射率

1.578

合成路线

378-44-9

倍他米松

79578-14-6

[(8S,10S,11S,13S,14S,16S)-9-氟-11-羟基-10,13,16-三甲基-17-甲硫基羰基-3-氧代-6,7,8,11,12,14,15,16-八氢环戊烯并[a]菲-17-基]乙酸酯

上游原料

(8S,10S,11S,13S,14S,16S)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid

5188-07-8

甲硫醇钠

37927-21-2

17α-acetoxy-9α-fluoro-11β-hydroxy-16β-methyl-3-oxoandrosta-1,4-diene-17β-carboxylic acid