化合物简介
Ketorfanol (INN, USAN) (developmental code name SBW-22), or ketorphanol, is an opioid analgesic of the morphinan family that was found to possess \"potent antiwrithing activity\" in animal assays but was never marketed. It is a 17-cycloalkylmethyl derivative of morphinan and as such, is closely related structurally to butorphanol, cyclorphan, oxilorphan, proxorphan, and xorphanol, which act preferentially as κ-opioid receptor agonists and to a lesser extent as μ-opioid receptor partial agonists/antagonists.
基本信息
中文名称
酮啡诺
英文名称
Ketorfanol
中文别名
英文别名
UNII-8Z0ZXE70XL、17-cyclopropylmethyl-4-hydroxymorphinan-6-one、SBW-22
CAS号
79798-39-3
分子式
C20H25NO2
分子量
311.418
精确质量
311.189
PSA
40.54
LOGP
2.9775
编号系统
UNII
8Z0ZXE70XL
物化性质
密度
1.26g/cm3
沸点
489.6ºC at 760 mmHg
闪点
249.9ºC
折射率
1.641
上游原料
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