百科

土槿皮乙酸

CAS号：82508-31-4

英文名：PSEUDOLARIC ACID B

分子式

C23H28O8

熔点

密度

1.29g/cm3

分子量

432.464

沸点

613.8ºC at 760 mmHg

溶解度

信号词

危险品标志

若想填写更详细的询价信息，请点击进入询价页面

点我

化合物简介

(-)-Pseudolaric Acid B is a diterpenoid posessing an immunomodulatory effect. It acts as an immunosuppressant in vitro/vivo however does show some cytotoxicity. Anti-tumor agent as well.

基本信息

中文名称

土槿皮乙酸

英文名称

PSEUDOLARIC ACID B

中文别名

土荆皮乙酸、土荆皮乙酸,土荆乙酸

英文别名

Pseudolarix acid B、PseudolaricAcid?B、PLAB

CAS号

82508-31-4

分子式

C23H28O8

分子量

432.464

精确质量

432.178

PSA

116.2

LOGP

2.8706

物化性质

密度

1.29g/cm3

沸点

613.8ºC at 760 mmHg

闪点

208.8ºC

折射率

1.565

合成路线

1000669-90-8

(1R,7S,8S,9S)-7-acetoxy-9-ethynyl-9-methyl-11-oxo-10-oxa-tricyclo[6.3.2.01,7]tridec-3-ene-4-carboxylic acid methyl ester

128836-43-1

3-iodo-2-methylprop-2-enoic acid

上游原料

(1R,7S,8S,9S)-7-acetoxy-9-ethynyl-9-methyl-11-oxo-10-oxa-tricyclo[6.3.2.01,7]tridec-3-ene-4-carboxylic acid methyl ester

457622-30-9

methyl (3R,4R,4aS,7S,9aR)-4a-hydroxy-3-methyl-1-oxo-3-((E)-3-oxoprop-1-en-1-yl)octahydro-1H-4,9a-ethanocyclohepta[c]pyran-7-carboxylate

128836-43-1

3-iodo-2-methylprop-2-enoic acid

457622-31-0

methyl (3R,4R,4aS,7S,9aR)-4a-hydroxy-3-((E)-3-hydroxyprop-1-en-1-yl)-3-methyl-1-oxooctahydro-1H-4,9a-ethanocyclohepta[c]pyran-7-carboxylate

457622-29-6

(1R,4S,7S,8R,9R)-7-Hydroxy-9-((1E,3E)-5-hydroxy-4-methyl-penta-1,3-dienyl)-9-methyl-11-oxo-10-oxa-tricyclo[6.3.2.01,7]tridecane-4-carboxylic acid methyl ester

457622-33-2

methyl (3S,4R,4aS,7S,9aR)-4a-acetoxy-3-formyl-3-methyl-1-oxooctahydro-1H-4,9a-ethanocyclohepta[c]pyran-7-carboxylate

上游原料

(1R,7S,8S,9S)-7-acetoxy-9-ethynyl-9-methyl-11-oxo-10-oxa-tricyclo[6.3.2.01,7]tridec-3-ene-4-carboxylic acid methyl ester methyl (3R,4R,4aS,7S,9aR)-4a-hydroxy-3-methyl-1-oxo-3-((E)-3-oxoprop-1-en-1-yl)octahydro-1H-4,9a-ethanocyclohepta[c]pyran-7-carboxylate 3-iodo-2-methylprop-2-enoic acid methyl (3R,4R,4aS,7S,9aR)-4a-hydroxy-3-((E)-3-hydroxyprop-1-en-1-yl)-3-methyl-1-oxooctahydro-1H-4,9a-ethanocyclohepta[c]pyran-7-carboxylate (1R,4S,7S,8R,9R)-7-Hydroxy-9-((1E,3E)-5-hydroxy-4-methyl-penta-1,3-dienyl)-9-methyl-11-oxo-10-oxa-tricyclo[6.3.2.01,7]tridecane-4-carboxylic acid methyl ester methyl (3S,4R,4aS,7S,9aR)-4a-acetoxy-3-formyl-3-methyl-1-oxooctahydro-1H-4,9a-ethanocyclohepta[c]pyran-7-carboxylate methyl (3R,4R,4aS,9aR)-4a-hydroxy-3-((1E,3E)-5-hydroxy-4-methylpenta-1,3-dien-1-yl)-3-methyl-1-oxo-3,4,4a,5,6,9-hexahydro-1H-4,9a-ethanocyclohepta[c]pyran-7-carboxylate methyl (3S,4R,4aS,7S,9aR)-3-formyl-4a-hydroxy-3-methyl-1-oxooctahydro-1H-4,9a-ethanocyclohepta[c]pyran-7-carboxylate