化合物简介
Naphazoline (in the hydrochloride form) is the common name for 2-(1-naphthylmethyl)-2-imidazoline hydrochloride. It is a sympathomimetic agent with marked alpha adrenergic activity. It is a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane. It acts on alpha-receptors in the arterioles of the conjunctiva to produce constriction, resulting in decreased congestion. It is an active ingredient in several over-the-counter formulations including Clear Eyes and Naphcon eye drops.
基本信息
中文名称
萘甲唑林
英文名称
2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole
中文别名
2-(1-萘甲)咪唑啉鹽酸鹽、2-(1-萘甲基)-4,5-二氢-1H-咪唑、萘达帕汀
英文别名
Naphthizine、Antan、Clearine、Nafazolina、naphazoline
CAS号
835-31-4
分子式
C14H14N2
分子量
210.274
精确质量
210.116
PSA
24.39
LOGP
2.1484
编号系统
UNII
H231GF11BV
物化性质
密度
1.15g/cm3
沸点
440.5ºC at 760 mmHg
熔点
254ºC
闪点
220.2ºC
折射率
1.64
安全信息
RTECS号
NJ4375000
安全说明
S45
WGK Germany
3
危险类别码
R25
危险品运输编码
UN 2811 6.1/PG 2
海关编码
2934999090
危险品标志
T
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