N-[(1-乙基-2-吡咯烷基)甲基]-2-羟基-3-碘-6-甲氧基-苯甲酰胺

CAS号：84226-06-2

英文名：BENZAMIDE, N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-HYDROXY-3-IODO-6-METHOXY-

分子式

C15H21IN2O3

熔点

密度

1.51 g/cm3

分子量

404.243

沸点

426.9ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

IBZM (abbreviation for iodobenzamide) is a chemical substance. Pharmaceutically it is a dopamine antagonist and it can be used by nuclear medicine physicians as a radioactive tracer for SPECT where the radioactive isotope is iodine-123 or iodine-125. The main purpose of a brain study with IBZM is the differentiation of Parkinson's disease from other neurodegenerative diseases such as Lewy Body dementia and multiple system atrophy.

基本信息

中文名称

N-[(1-乙基-2-吡咯烷基)甲基]-2-羟基-3-碘-6-甲氧基-苯甲酰胺

英文名称

BENZAMIDE, N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-HYDROXY-3-IODO-6-METHOXY-

中文别名

英文别名

IBZM、(s)-benzamid、N-[[(2S)-1-Ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-3-iodo-6-methoxybenzamide、S-(-)-IBZM、IODOBENZAMIDE,(S)-(-)-3-IODO-2-HYDROXY-6-METHOXY-N[(1-ETHYL-2-PYRROLIDINYL)METHYL]BENZAMIDE、3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide、[123I]-IBZM、(S)-N-(1-ethylpyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxybenzamide、(s)-n-(1-ethyl-2-pyrrolidinyl)methyl-2-hydroxy-3-iodo-6-methoxybenzamide、(S)-(-)-3-iodo-2-hydroxy-6-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide

CAS号

84226-06-2

分子式

C15H21IN2O3

分子量

404.243

精确质量

404.06

PSA

61.8

LOGP

2.5483