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N-Boc-2-甲基-D-丝氨酸

N-Boc-2-甲基-D-丝氨酸

CAS号：84311-18-2

英文名：(R)-2-((tert-Butoxycarbonyl)amino)-3-hydroxy-2-methylpropanoic acid

分子式

C9H17NO5

熔点

50 - 52 °C

密度

分子量

219.235

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

N-Boc-2-甲基-D-丝氨酸

英文名称

(R)-2-((tert-Butoxycarbonyl)amino)-3-hydroxy-2-methylpropanoic acid

中文别名

N-BOC-Alpha-甲基-D-丝氨酸

英文别名

(2R)-3-hydroxy-2-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid

CAS号

84311-18-2

分子式

C9H17NO5

分子量

219.235

精确质量

219.111

PSA

95.86

LOGP

0.7376

编号系统

MDL号

MFCD02682596

物化性质

熔点

50 - 52 °C

安全信息

海关编码

2924199090

合成路线

共找到55条合成路线 >

二碳酸二叔丁酯

二碳酸二叔丁酯

2-甲基-DL-丝氨酸水合物

2-甲基-DL-丝氨酸水合物

N-Boc-2-甲基-D-丝氨酸

N-Boc-2-甲基-D-丝氨酸

上游原料

共找到4个上游原料 >

二碳酸二叔丁酯

二碳酸二叔丁酯

(R)-3-acetoxy-2-((tert-butoxycarbonyl)amino)-2-methylpropanoic acid

(R)-3-acetoxy-2-((tert-butoxycarbonyl)amino)-2-methylpropanoic acid

2-甲基-DL-丝氨酸水合物

2-甲基-DL-丝氨酸水合物

tert-butyl (1-hydroxy-2-phenylpropan-2-yl)carbamate

tert-butyl (1-hydroxy-2-phenylpropan-2-yl)carbamate

下游产品

共找到56个下游商品 >

tert-butyl (R)-4-((1S,4S,5S)-7-(methoxycarbonyl)-3-oxo-2-oxabicyclo[2.2.2]oct-7-ene-5-carbonyl)-2,2-dimethyloxazolidine-3-carboxylate

tert-butyl (R)-4-((1S,4S,5S)-7-(methoxycarbonyl)-3-oxo-2-oxabicyclo[2.2.2]oct-7-ene-5-carbonyl)-2,2-dimethyloxazolidine-3-carboxylate

(4R,5R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-5-(3-methanesulfonyloxy-propyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

(4R,5R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-5-(3-methanesulfonyloxy-propyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

(R)-tert-butyl-3-(tert-butyldimethylsilyloxy)-1-oxo-1-phenylpropan-2-ylcarbamate

(R)-tert-butyl-3-(tert-butyldimethylsilyloxy)-1-oxo-1-phenylpropan-2-ylcarbamate

methyl (3R,4R,4aR,6R,8R,8aR)-4-allyl-6-((tert-butoxycarbonyl)amino)-1,7-dioxooctahydro-1H-3,8-methanoisochromene-4-carboxylate

methyl (3R,4R,4aR,6R,8R,8aR)-4-allyl-6-((tert-butoxycarbonyl)amino)-1,7-dioxooctahydro-1H-3,8-methanoisochromene-4-carboxylate

tert-butyl (1R,2S)-N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecynyl]-carbamate

tert-butyl (1R,2S)-N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecynyl]-carbamate

((R)-2-(4-Chloro-benzyloxy)-1-{[5-(4-chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-ethyl)-carbamic acid tert-butyl ester

((R)-2-(4-Chloro-benzyloxy)-1-{[5-(4-chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-ethyl)-carbamic acid tert-butyl ester

上游原料

二碳酸二叔丁酯 (R)-3-acetoxy-2-((tert-butoxycarbonyl)amino)-2-methylpropanoic acid 2-甲基-DL-丝氨酸水合物 tert-butyl (1-hydroxy-2-phenylpropan-2-yl)carbamate

下游产品

tert-butyl (R)-4-((1S,4S,5S)-7-(methoxycarbonyl)-3-oxo-2-oxabicyclo[2.2.2]oct-7-ene-5-carbonyl)-2,2-dimethyloxazolidine-3-carboxylate (4R,5R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-5-(3-methanesulfonyloxy-propyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester (R)-tert-butyl-3-(tert-butyldimethylsilyloxy)-1-oxo-1-phenylpropan-2-ylcarbamate methyl (3R,4R,4aR,6R,8R,8aR)-4-allyl-6-((tert-butoxycarbonyl)amino)-1,7-dioxooctahydro-1H-3,8-methanoisochromene-4-carboxylate tert-butyl (1R,2S)-N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecynyl]-carbamate ((R)-2-(4-Chloro-benzyloxy)-1-{[5-(4-chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-ethyl)-carbamic acid tert-butyl ester ((R)-2-(2-Chloro-6-fluoro-benzyloxy)-1-{[5-(4-chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-ethyl)-carbamic acid tert-butyl ester (R)-tert-butyl-3-(tert-butyldimethylsilyloxy)-1-oxo-1-(4-fluoro)phenylpropan-2-ylcarbamate (R)-tert-butyl-3-(tert-butyldimethylsilyloxy)-1-oxo-1-(4-methoxy)phenylpropan-2-ylcarbamate (R)-4-((R)-1-hydroxy-1-methylpropyl)-2,2-dimethyl oxazolidine-3-carboxylic acid tert-butyl ester [(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(3-fluoro-benzyloxy)-ethyl]-carbamic acid tert-butyl ester N-tert-butoxycarbonyl-β-iodo-(S)-alanine allyl ester (2R)-2-(tert-butoxycarbonylamino)-3-oxo-3-(4-methoxy)phenylpropyl acetate [(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2,3-difluoro-benzyloxy)-ethyl]-carbamic acid tert-butyl ester (4R,5R)-5-Allyl-4-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester (2R)-2-(tert-butoxycarbonyl-amino)-3-methoxy-N-[3-methyl-4-(3-oxo-morpholin-4-yl)-phenyl]-propionamide [(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2,5-difluoro-benzyloxy)-ethyl]-carbamic acid tert-butyl ester <N-(tert-butoxycarbonyl)-O-(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)-D-seryl>-L-glutamic acid 1-methylamide 5-benzyl ester ((R)-2-(4-Chloro-2-fluoro-benzyloxy)-1-{[5-(4-chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-ethyl)-carbamic acid tert-butyl ester [(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2-trifluoromethyl-benzyloxy)-ethyl]-carbamic acid tert-butyl ester (2R,3S)-1-(tert-butoxycarbonyl)-2-hydroxymethyl-3-[3-((Z)-2-iodovinyl)-4-methoxy-phenoxy]-pyrrolidine [(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(4-trifluoromethyl-benzyloxy)-ethyl]-carbamic acid tert-butyl ester [(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(4-cyano-benzyloxy)-ethyl]-carbamic acid tert-butyl ester [(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2,4,5-trifluoro-benzyloxy)-ethyl]-carbamic acid tert-butyl ester tert-butyl (R)-4-((1R,4R,5R)-7-(methoxycarbonyl)-3-oxo-2-oxabicyclo[2.2.2]oct-7-ene-5-carbonyl)-2,2-dimethyloxazolidine-3-carboxylate methyl (1R,4R,8R)-8-((S)-3-bromo-2-((tert-butoxycarbonyl)amino)propanoyl)-3-oxo-2-oxabicyclo[2.2.2]oct-5-ene-6-carboxylate [(R)-2-tert-Butoxycarbonylamino-3-(tert-butyl-diphenyl-silanyloxy)-propionylamino]-acetic acid allyl ester (2R)-2-(tert-butoxycarbonylamino)-3-oxo-3-phenylpropyl acetate methyl (3R,4R,4aR,8R,8aR)-4-allyl-6-((tert-butoxycarbonyl)amino)-1,7-dioxo-3,4,4a,7,8,8a-hexahydro-1H-3,8-methanoisochromene-4-carboxylate D-serine tert-butyl ester hydrochloride (4R,5R)-3-N-tert-butoxycarbonyl-4-tert-butyldiphenylsilyloxymethyl-5-<3''-hydroxypropyl>-2,2-dimethyl-1,3-oxazolidine tert-butyl N-(3-methyl-2-oxooxetan-3-yl)carbamate [(1R,2R)-1-(tert-Butyl-diphenyl-silanyloxymethyl)-2-hydroxy-pent-4-enyl]-carbamic acid tert-butyl ester [(R)-1-(tert-Butyl-dimethyl-silanyloxymethyl)-2-(2,2-dimethyl-4,6-dioxo-[1,3]dioxan-5-ylidene)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester N-tert-butoxycarbonyl-O-methanesulfonyl-(R)-serine allyl ester [(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2,6-difluoro-3-methyl-benzyloxy)-ethyl]-carbamic acid tert-butyl ester (E)-methyl 3-(4-((S)-2-((R)-2-((tert-butoxycarbonyl)amino)-3-hydroxypropanamido)-3-(1H-indol-3-yl)propoxy)phenyl)acrylate [(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2-fluoro-benzyloxy)-ethyl]-carbamic acid tert-butyl ester [(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(4-fluoro-benzyloxy)-ethyl]-carbamic acid tert-butyl ester (R)-2-tert-butoxycarbonylamino-3-(2-thien-3-ylethoxy)propionic acid methyl (1R,4R,8R)-8-((tert-butoxycarbonyl)-D-seryl)-3-oxo-2-oxabicyclo[2.2.2]oct-5-ene-6-carboxylate [(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2,3-dichloro-benzyloxy)-ethyl]-carbamic acid tert-butyl ester ((R)-2-(2-Chloro-4-fluoro-benzyloxy)-1-{[5-(4-chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-ethyl)-carbamic acid tert-butyl ester N-(tert-butoxycarbonyl)-D-serine hydroxamic acid [(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2,6-dichloro-benzyloxy)-ethyl]-carbamic acid tert-butyl ester ((R)-2-(2-Chloro-3,6-difluoro-benzyloxy)-1-{[5-(4-chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-ethyl)-carbamic acid tert-butyl ester (2R)-2-(tert-butoxycarbonylamino)-3-oxo-3-(4-methyl)phenylpropyl acetate [(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2-methyl-benzyloxy)-ethyl]-carbamic acid tert-butyl ester (4R)-3,5,5-trimethyl-4-[[(tetrahydro-2H-pyran-2-yl)oxy]methyl]-2-oxazolidinone