百科

2-溴-1-(4-氟苯基)-1-丁酮

CAS号：849217-64-7

英文名：N-(3-Fluoro-4-((6-methoxy-7-(3-morpholinopropoxy)quinolin-4-yl)-oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

分子式

C34H34F2N4O6

熔点

密度

1.372g/cm3

分子量

632.654

沸点

828.475ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

Foretinib is an experimental drug candidate for the treatment of cancer. It was discovered by Exelixis and is under development by GlaxoSmithKline. About 10 Phase II clinical trials have been run. As of October 2015[update] no phase III trials are registered.

基本信息

中文名称

2-溴-1-(4-氟苯基)-1-丁酮

英文名称

N-(3-Fluoro-4-((6-methoxy-7-(3-morpholinopropoxy)quinolin-4-yl)-oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

中文别名

N-[3-氟-4-[[6-甲氧基-7-[[3-(吗啉-4-基)丙基]氧]喹啉-4-基]氧]苯基]-N-(4-氟苯基)环丙烷-1,1-二甲酰胺

英文别名

4-(4-(o-Methoxyphenyl)piperazinyl)-1-(3,4,5-trimethoxyphenyl)-1-butanol dihydrochloride、4-[4-(2-methoxyphenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-ol dihydrochloride、Foretinib、4-(4-Hydroxy-4-(3,4,5-trimethoxyphenyl)butyl)-1-(o-methoxyphenyl)piperazine dihydrochloride、N1-{3-fluoro-4-[(6-(methyloxy)-7-{[3-(4-morpholinyl)propyl]oxy}-4-quinolinyl)oxy]phenyl}-N1\'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide、N-[3-fluoro-4-([6-(methyloxy)-7-[(3-morpholin-4-ylpropyl)oxy]quinolin-4-yl]oxy)phenyl]-N\'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide、1-Butanol,4-(4-(o-methoxyphenyl)piperazinyl)-1-(3,4,5-trimethoxyphenyl)-,dihydrochloride

CAS号

849217-64-7

分子式

C34H34F2N4O6

分子量

632.654

精确质量

632.245

PSA

116.45

LOGP

5.9834