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甲基泼尼松龙乙丙酸酯

甲基泼尼松龙乙丙酸酯

CAS号：86401-95-8

英文名：Methylprednisolone aceponate

分子式

C27H36O7

熔点

密度

1.23 g/cm3

分子量

472.571

沸点

595.8ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

Used in treatment of seborrhoeic dermatitis includes topical treatments such as corticosteroids, antifungals, metronidazole and pimecrolimus.

基本信息

中文名称

甲基泼尼松龙乙丙酸酯

英文名称

Methylprednisolone aceponate

中文别名

甲泼尼龙醋丙酯、6-Alpha-甲基泼尼松龙醋丙酯、醋丙甲泼尼龙、(6Α,11Β)-21-(乙酰氧基)-11-羟基-6-甲基-17-(1-氧代丙氧基)孕甾-1,4-二烯-3,20-二酮、醋丙酸甲基泼尼松龙

英文别名

Methylprednisoloni aceponas [Latin]、Aceponato de metilprednisolona [Spanish]、Advantan、SH-440、Aceponate de methylprednisolone [French]、[(6S,8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-11-hydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl] propanoate、Methylprednisolone aceponate

CAS号

86401-95-8

分子式

C27H36O7

分子量

472.571

精确质量

472.246

PSA

106.97

LOGP

3.3353

编号系统

UNII

ET54W9J4U2

物化性质

密度

1.23 g/cm3

沸点

595.8ºC at 760 mmHg

闪点

193.1ºC

折射率

1.559

合成路线

21-acetoxy-6α-methyl-17-propionyloxy-11β-trifluoroacetoxy-1,4-pregnadiene-3,20-dione

21-acetoxy-6α-methyl-17-propionyloxy-11β-trifluoroacetoxy-1,4-pregnadiene-3,20-dione

甲基泼尼松龙乙丙酸酯

甲基泼尼松龙乙丙酸酯

上游原料

共找到6个上游原料 >

11β,21-dihydroxy-6α-methyl-17α-propionyloxy-1,4-pregnadiene-3,20-dione

11β,21-dihydroxy-6α-methyl-17α-propionyloxy-1,4-pregnadiene-3,20-dione

21-acetoxy-6α-methyl-17-propionyloxy-11β-trifluoroacetoxy-1,4-pregnadiene-3,20-dione

21-acetoxy-6α-methyl-17-propionyloxy-11β-trifluoroacetoxy-1,4-pregnadiene-3,20-dione

乙酸酐

(6S,8S,9S,10R,11S,13S,14S,17R)-2'-ethyl-11-hydroxy-2'-methoxy-6,10,13-trimethyl-7,8,9,10,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,4'-[1,3]dioxane]-3,5'(6H)-dione

(6S,8S,9S,10R,11S,13S,14S,17R)-2'-ethyl-11-hydroxy-2'-methoxy-6,10,13-trimethyl-7,8,9,10,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,4'-[1,3]dioxane]-3,5'(6H)-dione

17α,21-diacetoxy-11β-hydroxy-6α-methyl-1,4-pregnadiene-3,20-dione

17α,21-diacetoxy-11β-hydroxy-6α-methyl-1,4-pregnadiene-3,20-dione

6α-Methylprednisolone 17α,21-ethyl orthopropanoate

6α-Methylprednisolone 17α,21-ethyl orthopropanoate

上游原料

11β,21-dihydroxy-6α-methyl-17α-propionyloxy-1,4-pregnadiene-3,20-dione 21-acetoxy-6α-methyl-17-propionyloxy-11β-trifluoroacetoxy-1,4-pregnadiene-3,20-dione 乙酸酐 (6S,8S,9S,10R,11S,13S,14S,17R)-2'-ethyl-11-hydroxy-2'-methoxy-6,10,13-trimethyl-7,8,9,10,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,4'-[1,3]dioxane]-3,5'(6H)-dione 17α,21-diacetoxy-11β-hydroxy-6α-methyl-1,4-pregnadiene-3,20-dione 6α-Methylprednisolone 17α,21-ethyl orthopropanoate