化合物简介
Homatropine (Equipin, Isopto Homatropine) is an anticholinergic medication that is an antagonist at muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It is used in eye drops as a cycloplegic (to temporarily paralyze accommodation), and as a mydriatic (to dilate the pupil). For Homatropine methylbromide see Methylhomatropine, this is a different medication. Homatropine is less potent than atropine and has a shorter duration of action. It is available as the hydrobromide salt.
基本信息
中文名称
后马托品
英文名称
[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2-phenylacetate
中文别名
扁桃酰托品碱、8-甲基-8-氮杂双环[3.2.1]辛烷-3-醇羟基(苯基)乙酸酯
英文别名
Omatropina [DCIT]、Homatropin、Homotropine、DL-mandelic acid-tropane-3endo-yl ester、Homoatropine、homatropine、Mandelyltropeine、Homatropine [BAN]、Benzeneacetic acid, α-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-(±)-、Methylhomatropinum、homatropine hydrobromide、8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester、DL-Mandelsaeure-tropan-3endo-ylester、Mandelytropeine
CAS号
87-00-3
分子式
C16H21NO3
分子量
275.343
精确质量
275.152
PSA
49.77
LOGP
1.8263
编号系统
UNII
8QS6WCL55Z
物化性质
密度
1.21 g/cm3
沸点
403.3ºC
熔点
100ºC
闪点
197.7ºC
安全信息
海关编码
2933990090
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