百科

[(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2-methyl-benzyloxy)-ethyl]-carbamic acid tert-butyl ester

[(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2-methyl-benzyloxy)-ethyl]-carbamic acid tert-butyl ester

CAS号：872413-97-3

英文名：[(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2-methyl-benzyloxy)-ethyl]-carbamic acid tert-butyl ester

分子式：C30H40ClN3O6S

分子量：606.173

合成路线

[5-(4-chlorophenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydroisothiazol-4-ylmethyl]ethylamine

[5-(4-chlorophenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydroisothiazol-4-ylmethyl]ethylamine

N-tert-butoxycarbonylamino-O-(2-methylbenzyl)-D-serine

N-tert-butoxycarbonylamino-O-(2-methylbenzyl)-D-serine

[(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2-methyl-benzyloxy)-ethyl]-carbamic acid tert-butyl ester

[(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2-methyl-benzyloxy)-ethyl]-carbamic acid tert-butyl ester

N-Boc-2-甲基-D-丝氨酸

N-Boc-2-甲基-D-丝氨酸

[(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2-methyl-benzyloxy)-ethyl]-carbamic acid tert-butyl ester

[(R)-1-{[5-(4-Chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-2-(2-methyl-benzyloxy)-ethyl]-carbamic acid tert-butyl ester

上游原料

N-Boc-2-甲基-D-丝氨酸 [5-(4-chlorophenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydroisothiazol-4-ylmethyl]ethylamine N-tert-butoxycarbonylamino-O-(2-methylbenzyl)-D-serine

下游产品

(R)-2-Amino-N-[5-(4-chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ6-isothiazol-4-ylmethyl]-N-ethyl-3-(2-methyl-benzyloxy)-propionamide