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(3S,4S)-3-[(R)-1-(叔丁基二甲基硅氧基)乙基]-4-[(R)-1-羰乙基]-2-氮杂环丁酮

(3S,4S)-3-[(R)-1-(叔丁基二甲基硅氧基)乙基]-4-[(R)-1-羰乙基]-2-氮杂环丁酮

CAS号:90776-58-2
英文名:Side chain for imipenem
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用途
用于合成美罗培南。
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(3S,4S)-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-1-[[(p-nitrobenzyl)oxy]oxalyl]-4-[(R)-1-[[(R)-2-oxopyrrolidin-4-ylthio]carbonyl]ethyl]-2-azetidinone 4-nitrobenzyl 2-((3S,4S)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-2-oxo-4-((R)-1-oxo-1-(((R)-5-oxopyrrolidin-3-yl)thio)propan-2-yl)azetidin-1-yl)-2-(triethoxy-l5-phosphaneylidene)acetate pivaloyloxymethyl (1R,5S,6S)-6-[(1R)-1-(tert-butyldimethylsilyloxy)ethyl]-2-[(3S,5S)-5-(N,N-dimethylcarbamoyl)-1-(isobutyryloxymethyloxycarbonyl)pyrrolidin-3-ylthio]-1-methylcarbapen-2-em-3-carboxylate (1R,5R,6S)-2-<4'-(aminomethyl)phenyl>-6-<(1R)-1-hydroxyethyl>-1-methylcarbapen-2-em-3-carboxylic acid 杂氮双环磷酸酯 (4R,5S,6S)-4-Methyl-7-oxo-3-((R)-5-oxo-1-triethylsilanyl-pyrrolidin-3-ylsulfanyl)-6-((R)-1-trimethylsilanyloxy-ethyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester (3S,4S)-4-[(R)-1-[[(R)-2-oxo-1-(triethylsilyl)pyrrolidin-4-ylthio]carbonyl]ethyl]-1-[[(pivaloyloxy)methyloxy]oxalyl]-3-[(R)-1-(trimethylsilyloxy)ethyl]-2-azetidinone 4-nitrobenzyl 2-((3S,4S)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-2-oxo-4-((R)-1-oxo-1-(((R)-5-oxopyrrolidin-3-yl)thio)propan-2-yl)azetidin-1-yl)-2-(diethoxy(ethyl)-l5-phosphaneylidene)acetate (3S,4S)-3-<(tert-butyldimethylsiloxy)methyl>-4-<1(R)-(methoxycarbonyl)ethyl>azetidin-2-one (R)-2-[(2S,3S)-4-Oxo-3-((R)-1-triethylsilanyloxy-ethyl)-azetidin-2-yl]-thiopropionic acid S-((R)-5-oxo-1-triethylsilanyl-pyrrolidin-3-yl) ester [(3S,4S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-oxo-4-((R)-1-phenylsulfanylcarbonyl-ethyl)-azetidin-1-yl]-acetic acid allyl ester potassium (1R,5R,6S)-2-(3'-pyridyl)-6-<(1R)-1-hydroxyethyl>-1-methylcarbapen-2-em-3-carboxylate (3S,4S)-3-[(R)-1-[[(R)-2-oxopyrrolidin-4-ylthio]carbonyl]ethyl]-3-[(R)-1-(triethylsilyloxy)ethyl]-2-azetidinone (R)-2-[(2S,3S)-3-((S)-1-Hydroxy-ethyl)-4-oxo-azetidin-2-yl]-propionic acid benzyl ester potassium (1R,5R,6S)-2-<4'-(hydroxymethyl)phenyl>-6-<(1R)-1-hydroxyethyl>-1-methylcarbapen-2-em-3-carboxylate (2S,5R,6S,7S)-7-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-5-methyl-4,8-dioxo-3-thia-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester (3S,4S)-3-[(R)-1-[[(R)-2-oxopyrrolidin-4-ylthio]carbonyl]ethyl]-3-[(R)-1-(trimethylsilyloxy)ethyl]-2-azetidinone (4S,5R,6S)-6-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-3-[1,3]dithian-2-ylidene-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester (2-(diethoxy(ethyl)-l5-phosphaneylidene)-2-((3S,4S)-2-oxo-4-((R)-1-oxo-1-(((R)-5-oxo-1-(triethylsilyl)pyrrolidin-3-yl)thio)propan-2-yl)-3-((R)-1-((trimethylsilyl)oxy)ethyl)azetidin-1-yl)acetoxy)methyl pivalate pivaloyloxymethyl (4R)-{(2R,3S)-3-[(1R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-oxoazetidin-2-y}-2-diaza-3-oxopentanoate (3S,4S)-1-(allyloxycarbonylmethyl)-3-[(1R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-[(1R)-1-carboxyethyl]-2-azetidinone pivaloyloxymethyl (4R)-{(2R,3S)-3-[(1R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-oxoazetidin-2-y}-3-oxopentanoate potassium (1R,5R,6S)-2-phenyl-6-<(1R)-1-hydroxyethyl>-1-methylcarbapen-2-em-3-carboxylate