化合物简介
Mepyramine, also known as pyrilamine, is a first generation antihistamine, targeting the H1 receptor. However, it rapidly permeates the brain often causing drowsiness. It also has anticholinergic properties. It is used in over-the-counter combination products to treat the common cold and menstrual symptoms. It is also the active ingredient of the topical antihistamine creams Anthisan and Neoantergan, sold for the treatment of insect bites, stings, and nettle rash.
基本信息
中文名称
美吡拉敏
英文名称
mepyramine
中文别名
英文别名
Pyranisamine、Anhistabs、N-[(4-methoxyphenyl)methyl]-N\',N\'-dimethyl-N-2-pyridinyl-1,2-ethanediamine、Dorantamin、Mepiramine、Antallergan、pyrilamine、Histapyran、N\'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N\'-pyridin-2-ylethane-1,2-diamine、Neoantergan、Antalergan、[13C]-Pyrilamine、Mepyramine(R)、1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N‘,N‘-dimethyl-N-2-pyridinyl-、Mepyramine
CAS号
91-84-9
分子式
C17H23N3O
分子量
285.384
精确质量
285.184
PSA
28.6
LOGP
2.6584
编号系统
MDL号
MFCD00023451
物化性质
沸点
201ºC at 5 MM HG