百科

2’,3’-二脱氧-3’-氟鸟苷

CAS号：92562-88-4

英文名：2-amino-9-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one

分子式

C10H12FN5O3

熔点

密度

2.01g/cm3

分子量

269.232

沸点

633.5ºC at 760mmHg

溶解度

信号词

危险品标志

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基本信息

中文名称

2’,3’-二脱氧-3’-氟鸟苷

英文名称

2-amino-9-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one

中文别名

2\',3\'-二脱氧-3\'-氟鸟苷、2`,3`-二脱氧-3`-氟鸟苷

英文别名

UNII-UU109JJU0U、Guanosine,2\',3\'-dideoxy-3\'-fluoro、Fddguo、3\'-FddG、3\'-fluoro-2\',3\'-dideoxyguanosine、2\',3\'-Dideoxy-3\'-fluoroguanosine、3\'-fluoro-3\'-deoxyguanosine

CAS号

92562-88-4

分子式

C10H12FN5O3

分子量

269.232

精确质量

269.092

PSA

119.05

LOGP

-0.0991

编号系统

UNII

UU109JJU0U

物化性质

密度

2.01g/cm3

沸点

633.5ºC at 760mmHg

闪点

336.9ºC

合成路线

1393669-10-7

上游原料

9-(5-O-benzoyl-2-deoxy-β-D-threo-pentofuranosyl)guanine

566202-24-2

2,3-dideoxy-3-fluoro-5-O-(4-phenylbenzoyl)-α-D-erythro-pentofuranosyl chloride

69370-84-9

2'-O-tosylguanosine

116002-28-9

9-(2-deoxy-α-L-erythro-pentofuranosyl)guanine

37070-11-4

8,2'-anhydro-8-mercaptoguanosine

873666-41-2

((2R,3R,4R,5R)-5-(2-acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-bromo-3-fluorotetrahydrofuran-2-yl)methyl acetate

上游原料

9-(5-O-benzoyl-2-deoxy-β-D-threo-pentofuranosyl)guanine 2,3-dideoxy-3-fluoro-5-O-(4-phenylbenzoyl)-α-D-erythro-pentofuranosyl chloride 2'-O-tosylguanosine 9-(2-deoxy-α-L-erythro-pentofuranosyl)guanine 8,2'-anhydro-8-mercaptoguanosine ((2R,3R,4R,5R)-5-(2-acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-bromo-3-fluorotetrahydrofuran-2-yl)methyl acetate 2-amino-6-chloro-9-(2-O-tosyl-β-D-ribofuranosyl)purine N-(6-氯-9h-嘌呤-2-基)乙酰胺 6-氯鸟嘌呤核苷 ((2R,3S)-5-acetoxy-3-fluorotetrahydrofuran-2-yl)methyl [1,1'-biphenyl]-4-carboxylate N2,5'-O-ditrityl-3' α-fluoro-2',3'-dideoxyguanosine N2,5'-O-ditrityl-8,2'-anhydro-3'-deoxy-3'-fluoro-8-mercapto-9-β-arabinofuranosylguanine N2,5'-O-ditrityl-8,2'-anhydro-8-mercapto-9-β-arabinofuranosylguanine 5'-O-benzoyl-3'-fluoro-2',3'-dideoxyguanosine N2-acetyl-2'-O-tosyl-2,6-diamino-9-β-D-ribofuranosylpurine 2,6-二氨基嘌呤核苷鸟苷 2-amino-6-chloro-9-(2,3-dideoxy-3-fluoro-β-D-erythro-pentofuranosyl)purine 2,3-dideoxy-3-fluoro-5-O-(4-phenylbenzoyl)-D-erythropentofuranosyl chloride 9-(5-pivaloyl-3-fluoro-2,3-dideoxy-β-D-ribofuranosyl)-2-acetamido-6-chloropurine 2-amino-6-chloro-9-(2-deoxy-β-D-threo-pentofuranosyl)purine 6-chloro-9-(5-O-trityl-2,3-dideoxy-3-fluoro-β-D-erythro-pentofuranosyl)-2-tritylaminopurine 甲基2,3-二脱氧-3-氟-5-O-(4-苯基苯甲酰基)-α-D-赤型-呋喃戊糖苷 methyl 2,3-dideoxy-3-fluoro-5-O-(4-phenylbenzoyl)-erythro-pentofuranoside 6-chloro-9-(5-O-trityl-2-deoxy-β-D-threo-pentofuranosyl)-2-tritylaminopurine