(7S,9S)-7-[(2R,3R,4R,5R,6S)-4,5-二羟基-3-碘-6-甲基氧杂环己-2-基]氧基-6,9,11-三羟基-9-(2-羟基乙酰基)-8,10-二氢-7H-并四苯-5,12-二酮_CAS号:92689-49-1

化合物简介

Annamycin is an anthracycline antibiotic being investigated for the treatment of cancer.

基本信息

中文名称

(7S,9S)-7-[(2R,3R,4R,5R,6S)-4,5-二羟基-3-碘-6-甲基氧杂环己-2-基]氧基-6,9,11-三羟基-9-(2-羟基乙酰基)-8,10-二氢-7H-并四苯-5,12-二酮

英文名称

annamycin

中文别名

英文别名

(7S,9S)-7-[(2R,3R,4R,5R,6S)-4,5-Dihydroxy-3-iodo-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-8,10-dihydro-7H-tetracene-5,12-dione

CAS号

92689-49-1

分子式

C26H25IO11

分子量

640.375

精确质量

640.044

PSA

191.05

LOGP

0.4398

编号系统

UNII

SNU299M83Q

物化性质

密度

1.94g/cm3

沸点

822.1ºC at 760 mmHg

闪点

451ºC

折射率

1.763

合成路线

92689-48-0

(7S,9S)-14-O-(tert-butyldimethylsilyl)-4-demethoxy-7-O-(2,6-dideoyxy-2-iodo-α-L-mannopyranosyl)adriamycinone

92689-49-1

(7S,9S)-7-[(2R,3R,4R,5R,6S)-4,5-二羟基-3-碘-6-甲基氧杂环己-2-基]氧基-6,9,11-三羟基-9-(2-羟基乙酰基)-8,10-二氢-7H-并四苯-5,12-二酮

上游原料

共找到6个上游原料 >

81979-75-1

(+/-)-14-bromo-4-demethoxydaunomycinone

92689-46-8

14-O-(tert-butyldimethylsilyl)-4-demethoxyadriamycinone

92761-44-9

(7S,9S)-14-O-(tert-butyldimethylsilyl)-4-demethoxy-7-O-(3,4-di-O-acetyl-2,6-dideoxy-2-iodo-α-L-mannopyranosyl)adriamycinone

73983-23-0

(2S,3S,4S,5R,6R)-5,6-dihydroxy-2-methyltetrahydro-2H-pyran-3,4-diyl diacetate

92689-48-0

(7S,9S)-14-O-(tert-butyldimethylsilyl)-4-demethoxy-7-O-(2,6-dideoyxy-2-iodo-α-L-mannopyranosyl)adriamycinone

65818-86-2

4-demethoxyadriamycinone