化合物简介
15-Hydroxyicosatetraenoic acid (also termed 15-HETE, 15(S)-HETE, and 15S-HETE) is an endogenous eicosanoid, i.e. a metabolite of arachidonic acid. Various cell types and tissues first produce 15-Hydroperoxyicosatetraenoic acid (15-HpETE). These initial hydroperoxy products are extremely short lived in cells: if not otherwise metabolized, they are reduced to 15-HETE. Both these molecules are are hormone-like autocrine and paracrine signalling agents, involved in inflammation response, but often are further metabolized to a wide range of products that are much more potent, including eoxins.
基本信息
中文名称
(15S,5Z,8Z,11Z,13E)-15-羟基二十碳四烯酸
英文名称
15(S)-HETE
中文别名
英文别名
15(S)-Hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid、(5Z,8Z,11Z,13E,15S)-15-hydroxyicosa-5,8,11,13-tetraenoic acid
CAS号
54845-95-3
分子式
C20H32O3
分子量
320.466
精确质量
320.235
PSA
57.53
LOGP
5.1875
编号系统
UNII
44JHK6G39Q
物化性质
密度
0.984 g/cm3
沸点
487.7ºC at 760 mmHg
闪点
262.8ºC
折射率
1.513
储存条件
-20ºC
安全信息
安全说明
7-16-26-36
危险类别码
R11
海关编码
2918199090
危险品运输编码
UN 1170 3
危险品标志
F; Xi
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