2,3,4,5-四氢-2,8-二甲基-5-[2-(6-甲基吡啶-3-基)乙基]-1H-吡啶并[4,3-b]吲哚

CAS号：3613-73-8

英文名：2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole

分子式

C21H25N3

熔点

密度

1.13 g/cm3

分子量

319.443

沸点

505.7ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

Latrepirdine (INN, also known as dimebolin and sold as Dimebon), is an antihistamine drug which has been used clinically in Russia since 1983.

基本信息

中文名称

2,3,4,5-四氢-2,8-二甲基-5-[2-(6-甲基吡啶-3-基)乙基]-1H-吡啶并[4,3-b]吲哚

英文名称

2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole

中文别名

2,3,4,5-四氢-2,8-二甲基-5-[2-(6-甲基吡啶-3-基)乙基]-1H-吡啶并[4,3-B]吲哚、丹吡芙蓉

英文别名

aka latrepiridine、Preparation 84、Dimebolin、Dimeboline、Dimebon、Latrepirdine、Dimebone

CAS号

3613-73-8

分子式

C21H25N3

分子量

319.443

精确质量

319.205

PSA

21.06

LOGP

3.8216

编号系统

UNII

OD9237K1Z6

物化性质

密度

1.13 g/cm3

沸点

505.7ºC at 760 mmHg

闪点

259.7ºC

合成路线

140-76-1

2-甲基-5-乙烯基吡啶

19686-05-6

2,8-二甲基-2,3,4,5-四氢-1H-吡啶并[4,3-b]吲哚

3613-73-8

2,3,4,5-四氢-2,8-二甲基-5-[2-(6-甲基吡啶-3-基)乙基]-1H-吡啶并[4,3-b]吲哚

上游原料

3-(2-amino-5-methylphenyl)pyridine

上游原料

吡啶-3-硼酸对甲苯胺 3-(2-amino-5-methylphenyl)pyridine 6-甲基烟酸甲酯 5-乙酰基-2-甲基吡啶对甲基苯肼 N'-(1-methyl-piperidin-4-ylidene)-N-[2-(6-methyl-pyridin-3-yl)-ethyl]-N-p-tolyl-hydrazine 2-(6-methylpyridin-3-yl)acetic acid N-(p-tolyl)amide 5-溴-2-甲基吡啶 4-methyl-N-[2-(6-methylpyridin-3-yl)ethyl]-N-nitrosoaniline 2,8-二甲基-2,3,4,5-四氢-1H-吡啶并[4,3-b]吲哚 1-(4-methylphenyl)-1-[2-(6-methylpyridin-3-yl)ethyl]hydrazine N-甲基-4-哌啶酮 3-(2-azido-5-methylphenyl)pyridine 2,8-dimethyl-5H-pyrido[4,3-b]indol-2-ium trifluoromethanesulfonate 1-methyl-3-(2-azido-5-methylphenyl)pyridinium triflate 4-[(6-methyl-pyridin-3-yl)-thioacetyl]-morpholine 2-甲基-5-乙烯基吡啶 6-甲基-3-吡啶乙醇 2-(6-甲基吡啶-3-基)乙酸 tert-butyl 8-methyl-5-(2-(6-methylpyridin-3-yl)ethyl)-3,4-dihydro-1H-pyrido[4,3-b]indole-2(5H)-carboxylate 2-溴-4-甲基苯胺 [2-acetyloxy-2-(2,2-dimethyl-6-phenylmethoxy-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethyl] acetate 对甲苯肼盐酸盐