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(2S,3R,4E)-2-叠氮-4-十八碳烯-1,3-二醇

(2S,3R,4E)-2-叠氮-4-十八碳烯-1,3-二醇

CAS号：103348-49-8

英文名：(2S,3R,4E)-2-AZIDO-4-OCTADECENE-1,3-DIOL

分子式

C18H35N3O2

熔点

53-54ºC

密度

分子量

325.489

沸点

溶解度

信号词

危险品标志

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化合物简介

A derivative of Sphingosine, a selective inhibitor of protein kinase C activity and phorbol dibutyrate binding in vitro in human platelets; does not inhibit protein kinase A or myosin light chain kinase; inhibits calmodulin-dependent enzymes; natural isomer of sphingosine.

基本信息

中文名称

(2S,3R,4E)-2-叠氮-4-十八碳烯-1,3-二醇

英文名称

(2S,3R,4E)-2-AZIDO-4-OCTADECENE-1,3-DIOL

中文别名

叠氮-赤-鞘氨醇

英文别名

(2S,3S,4E)-2-azidooctadec-1,3-O-di-(tert-butyl)-silanediyl-4-ene-1,3-diol、azidosphingosine、(2S,3R,4E)-2-azido-octadec-4-en-1,3-diol、D-erythro-azidophingosine、AZIDO-ERYTHRO-SPHINGOSINE、2-azidosphingosine、(2S,3R)-(E)-2-azidooctadec-4-ene-1,3-diol、D-SPHINGOSINE AZIDE

CAS号

103348-49-8

分子式

C18H35N3O2

分子量

325.489

精确质量

325.273

PSA

90.21

LOGP

4.72856

编号系统

MDL号

MFCD00274378

物化性质

外观与性状

白色至灰白色固体

熔点

53-54ºC

储存条件

-20ºC

安全信息

海关编码

2929909090

合成路线

共找到3条合成路线 >

D-鞘氨醇

(2S,3R,4E)-2-叠氮-4-十八碳烯-1,3-二醇

(2S,3R,4E)-2-叠氮-4-十八碳烯-1,3-二醇

上游原料

共找到55个上游原料 >

[(S)-2-azido-2-((4S,5R)-2,2-dioxo-5-tetradecyl-2λ6-[1,3,2]dioxathiolan-4-yl)ethoxy]-tert-butyldiphenylsilane

[(S)-2-azido-2-((4S,5R)-2,2-dioxo-5-tetradecyl-2λ6-[1,3,2]dioxathiolan-4-yl)ethoxy]-tert-butyldiphenylsilane

Phenyl 2,3,4-tris-O-(tert-butyldimethylsilyl)-1-thio-β-D-xylopyranoside

Phenyl 2,3,4-tris-O-(tert-butyldimethylsilyl)-1-thio-β-D-xylopyranoside

1,5-Anhydro-3,4-bis-O-(tert-butyldimethylsilyl)-2-deoxy-1-phenylsulfonyl-D-threo-pent-1-enitol

1,5-Anhydro-3,4-bis-O-(tert-butyldimethylsilyl)-2-deoxy-1-phenylsulfonyl-D-threo-pent-1-enitol

(4R,5S)-5-azido-4-((E)-pentadec-1-en-1-yl)-2-phenyl-1,3-dioxane

(4R,5S)-5-azido-4-((E)-pentadec-1-en-1-yl)-2-phenyl-1,3-dioxane

D-xylose-(2R,3R,4R)-5-di-O-isopropylidene-[4-(methylphenyl)sulfonyl]hydrazone

D-xylose-(2R,3R,4R)-5-di-O-isopropylidene-[4-(methylphenyl)sulfonyl]hydrazone

(2S,3S,4R)-2-叠氮基-1,3,4-十八烷三醇

(2S,3S,4R)-2-叠氮基-1,3,4-十八烷三醇

下游产品

共找到3个下游商品 >

2-叠氮基-1-特戊酰D-赤式-鞘氨醇

2-叠氮基-1-特戊酰D-赤式-鞘氨醇

N-(1,3-dihydroxyoctadec-4-en-2-yl)octadecanamide

N-(1,3-dihydroxyoctadec-4-en-2-yl)octadecanamide

D-鞘氨醇

上游原料

[(S)-2-azido-2-((4S,5R)-2,2-dioxo-5-tetradecyl-2λ6-[1,3,2]dioxathiolan-4-yl)ethoxy]-tert-butyldiphenylsilane Phenyl 2,3,4-tris-O-(tert-butyldimethylsilyl)-1-thio-β-D-xylopyranoside 1,5-Anhydro-3,4-bis-O-(tert-butyldimethylsilyl)-2-deoxy-1-phenylsulfonyl-D-threo-pent-1-enitol (4R,5S)-5-azido-4-((E)-pentadec-1-en-1-yl)-2-phenyl-1,3-dioxane D-xylose-(2R,3R,4R)-5-di-O-isopropylidene-[4-(methylphenyl)sulfonyl]hydrazone (2S,3S,4R)-2-叠氮基-1,3,4-十八烷三醇 (2R,3R,4E)-1,3-Di-O-benzoyloctadec-4-ene-1,2,3-triol (2S,3R)-(E)-2-azido-1-(tert-butyldiphenylsilyloxy)octadec-4-en-3-ol (2R,3R,4E)-1-tert-butyldimethylsilyloxy-3-(4-methoxybenzyl)-4-octadecen-2,3-diol (2R,3R,4E)-3-benzoyloxy-1,2-O-isopropylideneoctadec-4-ene-1,2-diol (2R,3R,4E)-2-Azido-1,3-di-O-benzoyloctadec-4-ene-1,3-diol (2R,3R,4E)-1,2-O-isopropylidene-3-hydroxy-4-octadecene-1,2-diol (2R,3R,4E)-octadec-4-ene-1,2,3-triol (2R,3R,E)-1-((tert-butyldimethylsilyl)oxy)-3-((4-methoxybenzyl)oxy)octadec-4-en-2-yl methanesulfonate D-鞘氨醇 (2S,3R,4E)-2-azido-1-tert-butyldimethylsilyloxy-4-octadecen-3-ol (2S,4R,5R)-4-((Z)-2-(tert-butyldimethylsilyl)pentadec-1-en-1-yl)-2-phenyl-1,3-dioxan-5-ol (2R,3R,4E)-1,3-O-isopropylidene-2-O-(methylsulfonyl)octadec-4-en-1,2,3-triol (2(R),3(R),4E)-1,3-O-isopropylidene-4-octadecene-1,2,3-triol (2S,3S,4R)-2-azido-1-(trityloxy)octadecane-3,4-diol (4S)-3-((2'R,3'R,4'E)-2'-azido-3'-hydroxy-4'-octadecenoyl)-4-(isopropyl)-2-oxazolidinone (2R,3R,Z)-5-(tert-butyldimethylsilyl)-2-((tert-butyldimethylsilyl)oxy)octadec-4-ene-1,3-diol 2,3,4-Tris-O-(tert-butyldimethylsilyl)-β-D-xylopyranosyl phenyl sulfone (2R,3R)-1,2-O-pentylidene-3-(4-methoxybenzyl)-(4E)-octadecen-1,2,3-triol (2S,3S,4R)-2-azido-1-(tert-butyldiphenylsilyloxy)octadecane-3,4-diol (2S,3R,4E)-2-叠氮-3-(叔丁基二甲基硅烷)-赤-鞘氨醇溴代十四烷 (2S,3R,4Z)-2-azido-octadec-4-ene-1,3-diol (2(S),3(R),4E)-2-azido-1,3-O-isopropylidene-4-octadecene-1,3-diol (2R,3R,4E)-3-(4'-methoxybenzyloxy)-4-octadecene-1,2-diol (2R,3R,4S)-1,3-O-isopropylidene-2,4-di-O-methylsulfonyl-5-hexen-1,2,3,4-tetrol (2R,3R,4E)-3-benzoyloxyoctadec-4-ene-1,2-diol (4S,5R)-4-((S)-1-azido-2-(trityloxy)ethyl)-5-tetradecyl-1,3,2-dioxathiolane 2,2-dioxide 2,3:4,5-二-O-(1-甲基乙亚基)-D-木糖 (2R,3R,4E)-1,3-Di-O-benzoyl-2-O-methylsulfonyloctadec-4-ene-1,2,3-triol (2R,3R)-trans-2-azide-1,3-O-benzylidene-1,3-octadec-4-enediol (2R,3R,4E)-1,3-benzylidene-2-methanesulfonyl-4-octadecene-1,2,3-triol (2R,3R,4S)-1,3-O-isopropylidene-5-hexen-1,2,3,4-tetrol (2S,3R,4E)-2-azido-1-tert-butyldimethylsilyloxy-3-(4-methoxybenzyl)-4-octadecen-3-ol (2S,3R,4E)-2-azido-3-benzoyloxy-4-octadecen-1-ol trans-2-hexadecenal (2S,3S,4E)-2-azidooctadec-1,3-O-di-(tert-butyl)silanediyl-4-ene-1,3-diol (2S,3S,4R)-2-azido-1,3-O-di-(tert-butyl)silanediyl-1,3,4-octadecanetriol (2S,4R,5R)-4-[(1E)-1-十五碳烯-1-基]-2-苯基-1,3-二恶烷-5-醇糖脂 3,5-O-isopropylidene-D-xylofuranose 正十四烷基三苯基溴化膦 (((3R,4R)-6-(phenylsulfinyl)-3,4-dihydro-2H-pyran-3,4-diyl)bis(oxy))bis(tert-butyldimethylsilane) (4S)-3-((2'S,3'R,4'E)-2'-bromo-3'-hydroxy-4-(isopropyl)-4'-octadecenoyl)-2-oxazolidinone

下游产品

2-叠氮基-1-特戊酰D-赤式-鞘氨醇 N-(1,3-dihydroxyoctadec-4-en-2-yl)octadecanamide D-鞘氨醇