化合物简介
BML-190 (Indomethacin morpholinylamide) is a drug used in scientific research that acts as a selective CB2 inverse agonist. BML-190 is structurally derived from the NSAID indomethacin but has a quite different biological activity. The activity produced by this compound is disputed, with some sources referring to it as a CB2 agonist rather than an inverse agonist; this may reflect an error in classification, or alternatively it may produce different effects in different tissues, and more research is required to resolve this dispute.
基本信息
中文名称
2-(1-(4-氯苯甲酰基)-5-甲氧基-2-甲基-1H-吲哚-3-基)-1-吗啉乙酮
英文名称
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-1-morpholin-4-ylethanone
中文别名
2-[1-(4-氯苯甲酰基)-5-甲氧基-2-甲基-1H-吲哚-3-基]-1-(4-吗啉基)乙酮
英文别名
Lopac-I-151、Indomethacin Morpholinylamide、Tocris-1383、Indomethacin morpholinamide、Indomethacin morpholinylamide、2-Methyl-5-methoxy-3-indolyl-essigsaeure-amid、IMMA、Ethanone (2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(4-morpholinyl)、BML-190
CAS号
2854-32-2
分子式
C23H23ClN2O4
分子量
426.893
精确质量
426.135
PSA
60.77
LOGP
3.6394
编号系统
MDL号
MFCD01317813
物化性质
密度
1.31g/cm3
沸点
586.7ºC at 760mmHg
闪点
308.6ºC
折射率
1.624
储存条件
2-8ºC
蒸汽压
8.34E-17mmHg at 25°C
安全信息
WGK Germany
3
海关编码
2934999090